HEAVY AND LIGHT CHAIN ALLOTYPIC MARKERS ON RABBIT HOMOCYTOTROPIC ANTIBODY

Evidence has been presented that rabbit homocytotropic antibody prepared against ovalbumin bears allotypic markers of both group a (heavy chain) and group b (light chain). This was shown by specific removal of activity in passive cutaneous anaphylaxis assays by anti-allotype immunoadsorbents. The ho...

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Detalles Bibliográficos
Autores principales: Kindt, T. J., Todd, C. W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1969
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138726/
https://www.ncbi.nlm.nih.gov/pubmed/4186445
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author Kindt, T. J.
Todd, C. W.
author_facet Kindt, T. J.
Todd, C. W.
author_sort Kindt, T. J.
collection PubMed
description Evidence has been presented that rabbit homocytotropic antibody prepared against ovalbumin bears allotypic markers of both group a (heavy chain) and group b (light chain). This was shown by specific removal of activity in passive cutaneous anaphylaxis assays by anti-allotype immunoadsorbents. The homocytotropic antibody has properties which indicate that it belongs to a new class of rabbit immunoglobulin. These results demonstrate that this newly described class possesses the allotypes of both groups a and b, as has been previously shown for other rabbit immunoglobulin classes.
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spelling pubmed-21387262008-04-17 HEAVY AND LIGHT CHAIN ALLOTYPIC MARKERS ON RABBIT HOMOCYTOTROPIC ANTIBODY Kindt, T. J. Todd, C. W. J Exp Med Article Evidence has been presented that rabbit homocytotropic antibody prepared against ovalbumin bears allotypic markers of both group a (heavy chain) and group b (light chain). This was shown by specific removal of activity in passive cutaneous anaphylaxis assays by anti-allotype immunoadsorbents. The homocytotropic antibody has properties which indicate that it belongs to a new class of rabbit immunoglobulin. These results demonstrate that this newly described class possesses the allotypes of both groups a and b, as has been previously shown for other rabbit immunoglobulin classes. The Rockefeller University Press 1969-10-01 /pmc/articles/PMC2138726/ /pubmed/4186445 Text en Copyright © 1969 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Kindt, T. J.
Todd, C. W.
HEAVY AND LIGHT CHAIN ALLOTYPIC MARKERS ON RABBIT HOMOCYTOTROPIC ANTIBODY
title HEAVY AND LIGHT CHAIN ALLOTYPIC MARKERS ON RABBIT HOMOCYTOTROPIC ANTIBODY
title_full HEAVY AND LIGHT CHAIN ALLOTYPIC MARKERS ON RABBIT HOMOCYTOTROPIC ANTIBODY
title_fullStr HEAVY AND LIGHT CHAIN ALLOTYPIC MARKERS ON RABBIT HOMOCYTOTROPIC ANTIBODY
title_full_unstemmed HEAVY AND LIGHT CHAIN ALLOTYPIC MARKERS ON RABBIT HOMOCYTOTROPIC ANTIBODY
title_short HEAVY AND LIGHT CHAIN ALLOTYPIC MARKERS ON RABBIT HOMOCYTOTROPIC ANTIBODY
title_sort heavy and light chain allotypic markers on rabbit homocytotropic antibody
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138726/
https://www.ncbi.nlm.nih.gov/pubmed/4186445
work_keys_str_mv AT kindttj heavyandlightchainallotypicmarkersonrabbithomocytotropicantibody
AT toddcw heavyandlightchainallotypicmarkersonrabbithomocytotropicantibody

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