IN VITRO INDUCTION OF A PRIMARY RESPONSE TO THE DINITROPHENYL DETERMINANT

Primary antibody response against the dinitrophenyl group has been elicited in vitro after the stimulation of normal mouse spleen explants with 2,4-dinitrophenyl (DNP)-hemocyanin or α-DNP-poly-L-lysine (PLL). Antibodies were detected in the culture medium by the inactivation of DNP-T4 phage. The spe...

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Detalles Bibliográficos
Autores principales: Segal, Shraga, Globerson, Amiela, Feldman, Michael, Haimovich, Joseph, Sela, Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1970
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138764/
https://www.ncbi.nlm.nih.gov/pubmed/5460614
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author Segal, Shraga
Globerson, Amiela
Feldman, Michael
Haimovich, Joseph
Sela, Michael
author_facet Segal, Shraga
Globerson, Amiela
Feldman, Michael
Haimovich, Joseph
Sela, Michael
author_sort Segal, Shraga
collection PubMed
description Primary antibody response against the dinitrophenyl group has been elicited in vitro after the stimulation of normal mouse spleen explants with 2,4-dinitrophenyl (DNP)-hemocyanin or α-DNP-poly-L-lysine (PLL). Antibodies were detected in the culture medium by the inactivation of DNP-T4 phage. The specificity of the reaction was manifested by the lack of the capacity of the medium to inactivate the unmodified bacteriophage and by the inhibition of the inactivation of DNP-T4 with DNP-lysine.
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spelling pubmed-21387642008-04-17 IN VITRO INDUCTION OF A PRIMARY RESPONSE TO THE DINITROPHENYL DETERMINANT Segal, Shraga Globerson, Amiela Feldman, Michael Haimovich, Joseph Sela, Michael J Exp Med Article Primary antibody response against the dinitrophenyl group has been elicited in vitro after the stimulation of normal mouse spleen explants with 2,4-dinitrophenyl (DNP)-hemocyanin or α-DNP-poly-L-lysine (PLL). Antibodies were detected in the culture medium by the inactivation of DNP-T4 phage. The specificity of the reaction was manifested by the lack of the capacity of the medium to inactivate the unmodified bacteriophage and by the inhibition of the inactivation of DNP-T4 with DNP-lysine. The Rockefeller University Press 1970-01-01 /pmc/articles/PMC2138764/ /pubmed/5460614 Text en Copyright © 1970 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Segal, Shraga
Globerson, Amiela
Feldman, Michael
Haimovich, Joseph
Sela, Michael
IN VITRO INDUCTION OF A PRIMARY RESPONSE TO THE DINITROPHENYL DETERMINANT
title IN VITRO INDUCTION OF A PRIMARY RESPONSE TO THE DINITROPHENYL DETERMINANT
title_full IN VITRO INDUCTION OF A PRIMARY RESPONSE TO THE DINITROPHENYL DETERMINANT
title_fullStr IN VITRO INDUCTION OF A PRIMARY RESPONSE TO THE DINITROPHENYL DETERMINANT
title_full_unstemmed IN VITRO INDUCTION OF A PRIMARY RESPONSE TO THE DINITROPHENYL DETERMINANT
title_short IN VITRO INDUCTION OF A PRIMARY RESPONSE TO THE DINITROPHENYL DETERMINANT
title_sort in vitro induction of a primary response to the dinitrophenyl determinant
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138764/
https://www.ncbi.nlm.nih.gov/pubmed/5460614
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AT globersonamiela invitroinductionofaprimaryresponsetothedinitrophenyldeterminant
AT feldmanmichael invitroinductionofaprimaryresponsetothedinitrophenyldeterminant
AT haimovichjoseph invitroinductionofaprimaryresponsetothedinitrophenyldeterminant
AT selamichael invitroinductionofaprimaryresponsetothedinitrophenyldeterminant

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