IN VITRO INTERACTION OF MOUSE HEPATITIS VIRUS AND MACROPHAGES FROM GENETICALLY RESISTANT MICE : I. ADSORPTION OF VIRUS AND GROWTH CURVES

Peritoneal macrophages from genetically resistant C(3)H mice and genetically susceptible Princeton (PRI) mice adsorbed the MHV (PRI) strain of mouse hepatitis virus equally well. The difference between the permissive cells and the nonpermissive ones seems to reside in the ability of the former to &q...

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Detalles Bibliográficos
Autores principales: Shif, Ilan, Bang, Frederik B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1970
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138781/
https://www.ncbi.nlm.nih.gov/pubmed/4317219
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author Shif, Ilan
Bang, Frederik B.
author_facet Shif, Ilan
Bang, Frederik B.
author_sort Shif, Ilan
collection PubMed
description Peritoneal macrophages from genetically resistant C(3)H mice and genetically susceptible Princeton (PRI) mice adsorbed the MHV (PRI) strain of mouse hepatitis virus equally well. The difference between the permissive cells and the nonpermissive ones seems to reside in the ability of the former to "eclipse" the virus and, subsequently, support virus replication. C(3)H cells exposed to low multiplicities of the virus remained intact with no demonstrable viral replication. Virus, taken up by the resistant cells, was protected from heat and underwent slow inactivation while few or no virus particles were released into the medium.
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spelling pubmed-21387812008-04-17 IN VITRO INTERACTION OF MOUSE HEPATITIS VIRUS AND MACROPHAGES FROM GENETICALLY RESISTANT MICE : I. ADSORPTION OF VIRUS AND GROWTH CURVES Shif, Ilan Bang, Frederik B. J Exp Med Article Peritoneal macrophages from genetically resistant C(3)H mice and genetically susceptible Princeton (PRI) mice adsorbed the MHV (PRI) strain of mouse hepatitis virus equally well. The difference between the permissive cells and the nonpermissive ones seems to reside in the ability of the former to "eclipse" the virus and, subsequently, support virus replication. C(3)H cells exposed to low multiplicities of the virus remained intact with no demonstrable viral replication. Virus, taken up by the resistant cells, was protected from heat and underwent slow inactivation while few or no virus particles were released into the medium. The Rockefeller University Press 1970-03-31 /pmc/articles/PMC2138781/ /pubmed/4317219 Text en Copyright © 1970 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Shif, Ilan
Bang, Frederik B.
IN VITRO INTERACTION OF MOUSE HEPATITIS VIRUS AND MACROPHAGES FROM GENETICALLY RESISTANT MICE : I. ADSORPTION OF VIRUS AND GROWTH CURVES
title IN VITRO INTERACTION OF MOUSE HEPATITIS VIRUS AND MACROPHAGES FROM GENETICALLY RESISTANT MICE : I. ADSORPTION OF VIRUS AND GROWTH CURVES
title_full IN VITRO INTERACTION OF MOUSE HEPATITIS VIRUS AND MACROPHAGES FROM GENETICALLY RESISTANT MICE : I. ADSORPTION OF VIRUS AND GROWTH CURVES
title_fullStr IN VITRO INTERACTION OF MOUSE HEPATITIS VIRUS AND MACROPHAGES FROM GENETICALLY RESISTANT MICE : I. ADSORPTION OF VIRUS AND GROWTH CURVES
title_full_unstemmed IN VITRO INTERACTION OF MOUSE HEPATITIS VIRUS AND MACROPHAGES FROM GENETICALLY RESISTANT MICE : I. ADSORPTION OF VIRUS AND GROWTH CURVES
title_short IN VITRO INTERACTION OF MOUSE HEPATITIS VIRUS AND MACROPHAGES FROM GENETICALLY RESISTANT MICE : I. ADSORPTION OF VIRUS AND GROWTH CURVES
title_sort in vitro interaction of mouse hepatitis virus and macrophages from genetically resistant mice : i. adsorption of virus and growth curves
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138781/
https://www.ncbi.nlm.nih.gov/pubmed/4317219
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