CHRONIC ALLOGENEIC DISEASE : II. DEVELOPMENT OF LYMPHOMAS

The incidence of lymphomas in 371 CAF(1) mice injected with BALB/c spleen cells was compared with that in 324 control CAF(1) mice. A high incidence of lymphomas was found in the treated mice, but not in the control animals. The development of the neoplasms was a function of the number of parental ce...

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Autores principales: Armstrong, Martine Y. K., Gleichmann, Ernst, Gleichmann, Helga, Beldotti, Lorraine, Andre-Schwartz, Janine, Schwartz, Robert S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1970
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138811/
https://www.ncbi.nlm.nih.gov/pubmed/5523966
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author Armstrong, Martine Y. K.
Gleichmann, Ernst
Gleichmann, Helga
Beldotti, Lorraine
Andre-Schwartz, Janine
Schwartz, Robert S.
author_facet Armstrong, Martine Y. K.
Gleichmann, Ernst
Gleichmann, Helga
Beldotti, Lorraine
Andre-Schwartz, Janine
Schwartz, Robert S.
author_sort Armstrong, Martine Y. K.
collection PubMed
description The incidence of lymphomas in 371 CAF(1) mice injected with BALB/c spleen cells was compared with that in 324 control CAF(1) mice. A high incidence of lymphomas was found in the treated mice, but not in the control animals. The development of the neoplasms was a function of the number of parental cells administered. Analyses of the injected mice for the presence of donor cells indicated that the majority of the injected parental cells lost antihost activity, probably within 24 hr of their administration. The tumors were of host origin, as judged by transplantation tests and antigenic analysis of tumor cells.
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spelling pubmed-21388112008-04-17 CHRONIC ALLOGENEIC DISEASE : II. DEVELOPMENT OF LYMPHOMAS Armstrong, Martine Y. K. Gleichmann, Ernst Gleichmann, Helga Beldotti, Lorraine Andre-Schwartz, Janine Schwartz, Robert S. J Exp Med Article The incidence of lymphomas in 371 CAF(1) mice injected with BALB/c spleen cells was compared with that in 324 control CAF(1) mice. A high incidence of lymphomas was found in the treated mice, but not in the control animals. The development of the neoplasms was a function of the number of parental cells administered. Analyses of the injected mice for the presence of donor cells indicated that the majority of the injected parental cells lost antihost activity, probably within 24 hr of their administration. The tumors were of host origin, as judged by transplantation tests and antigenic analysis of tumor cells. The Rockefeller University Press 1970-09-01 /pmc/articles/PMC2138811/ /pubmed/5523966 Text en Copyright © 1970 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Armstrong, Martine Y. K.
Gleichmann, Ernst
Gleichmann, Helga
Beldotti, Lorraine
Andre-Schwartz, Janine
Schwartz, Robert S.
CHRONIC ALLOGENEIC DISEASE : II. DEVELOPMENT OF LYMPHOMAS
title CHRONIC ALLOGENEIC DISEASE : II. DEVELOPMENT OF LYMPHOMAS
title_full CHRONIC ALLOGENEIC DISEASE : II. DEVELOPMENT OF LYMPHOMAS
title_fullStr CHRONIC ALLOGENEIC DISEASE : II. DEVELOPMENT OF LYMPHOMAS
title_full_unstemmed CHRONIC ALLOGENEIC DISEASE : II. DEVELOPMENT OF LYMPHOMAS
title_short CHRONIC ALLOGENEIC DISEASE : II. DEVELOPMENT OF LYMPHOMAS
title_sort chronic allogeneic disease : ii. development of lymphomas
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138811/
https://www.ncbi.nlm.nih.gov/pubmed/5523966
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