BACTERICIDAL SUBSTANCE FROM STAPHYLOCOCCUS AUREUS : BIOLOGICAL PROPERTIES

A bactericidal substance previously isolated from phage type 71 Slaphylococcus aureus has been further identified and characterized. Staphylococci belonging to phage type 71 produce the substance in higher titers than staphylococci lysed by other phages in group II in addition to phage 71. Other sta...

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Detalles Bibliográficos
Autores principales: Dajani, Adnan S., Gray, Ernest D., Wannamaker, Lewis W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1970
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138827/
https://www.ncbi.nlm.nih.gov/pubmed/5443199
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author Dajani, Adnan S.
Gray, Ernest D.
Wannamaker, Lewis W.
author_facet Dajani, Adnan S.
Gray, Ernest D.
Wannamaker, Lewis W.
author_sort Dajani, Adnan S.
collection PubMed
description A bactericidal substance previously isolated from phage type 71 Slaphylococcus aureus has been further identified and characterized. Staphylococci belonging to phage type 71 produce the substance in higher titers than staphylococci lysed by other phages in group II in addition to phage 71. Other staphylococci do not produce the bactericidal substance. The bactericidal substance shares several of the properties of bacteriocins but differs from this group of antibiotic substances in some respects. A combination of ammonium sulfate fractionation and gel filtration on a Sephadex G-100 column resulted in considerable degree of purification of the bactericidal substance. The substance is a previously unrecognized product of S. aureus and is distinct from other extracellular products of this organism.
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spelling pubmed-21388272008-04-17 BACTERICIDAL SUBSTANCE FROM STAPHYLOCOCCUS AUREUS : BIOLOGICAL PROPERTIES Dajani, Adnan S. Gray, Ernest D. Wannamaker, Lewis W. J Exp Med Article A bactericidal substance previously isolated from phage type 71 Slaphylococcus aureus has been further identified and characterized. Staphylococci belonging to phage type 71 produce the substance in higher titers than staphylococci lysed by other phages in group II in addition to phage 71. Other staphylococci do not produce the bactericidal substance. The bactericidal substance shares several of the properties of bacteriocins but differs from this group of antibiotic substances in some respects. A combination of ammonium sulfate fractionation and gel filtration on a Sephadex G-100 column resulted in considerable degree of purification of the bactericidal substance. The substance is a previously unrecognized product of S. aureus and is distinct from other extracellular products of this organism. The Rockefeller University Press 1970-05-01 /pmc/articles/PMC2138827/ /pubmed/5443199 Text en Copyright © 1970 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Dajani, Adnan S.
Gray, Ernest D.
Wannamaker, Lewis W.
BACTERICIDAL SUBSTANCE FROM STAPHYLOCOCCUS AUREUS : BIOLOGICAL PROPERTIES
title BACTERICIDAL SUBSTANCE FROM STAPHYLOCOCCUS AUREUS : BIOLOGICAL PROPERTIES
title_full BACTERICIDAL SUBSTANCE FROM STAPHYLOCOCCUS AUREUS : BIOLOGICAL PROPERTIES
title_fullStr BACTERICIDAL SUBSTANCE FROM STAPHYLOCOCCUS AUREUS : BIOLOGICAL PROPERTIES
title_full_unstemmed BACTERICIDAL SUBSTANCE FROM STAPHYLOCOCCUS AUREUS : BIOLOGICAL PROPERTIES
title_short BACTERICIDAL SUBSTANCE FROM STAPHYLOCOCCUS AUREUS : BIOLOGICAL PROPERTIES
title_sort bactericidal substance from staphylococcus aureus : biological properties
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138827/
https://www.ncbi.nlm.nih.gov/pubmed/5443199
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