THE IMMUNOGENICITY OF HUMAN HL-A HAPLOTYPES AS MEASURED BY SKIN GRAFT SURVIVAL TIMES AND MIXED LEUKOCYTE REACTIONS

The immunogenicity of the haplotypes in 30 families was measured by survival of skin grafts between selected paired family members. These families were genotyped for HL-A using 57 selected cytotoxic alloantisera defining HL-A 1–12 as well as other nondefined specificities. Mixed leukocyte reactions...

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Autores principales: Seigler, H. F., Ward, F. E., Amos, D. B., Phaup, M. B., Stickel, D. L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1971
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138954/
https://www.ncbi.nlm.nih.gov/pubmed/4939150
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author Seigler, H. F.
Ward, F. E.
Amos, D. B.
Phaup, M. B.
Stickel, D. L.
author_facet Seigler, H. F.
Ward, F. E.
Amos, D. B.
Phaup, M. B.
Stickel, D. L.
author_sort Seigler, H. F.
collection PubMed
description The immunogenicity of the haplotypes in 30 families was measured by survival of skin grafts between selected paired family members. These families were genotyped for HL-A using 57 selected cytotoxic alloantisera defining HL-A 1–12 as well as other nondefined specificities. Mixed leukocyte reactions were also studied in this series and the correlations between the mixed leukocyte reactions with skin graft survival times, individual HL-A specificities, and the number of incompatible HL-A alleles are reported. Comments concerning the interpretation and quantitation of the mixed leukocyte reactions are discussed.
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spelling pubmed-21389542008-04-17 THE IMMUNOGENICITY OF HUMAN HL-A HAPLOTYPES AS MEASURED BY SKIN GRAFT SURVIVAL TIMES AND MIXED LEUKOCYTE REACTIONS Seigler, H. F. Ward, F. E. Amos, D. B. Phaup, M. B. Stickel, D. L. J Exp Med Article The immunogenicity of the haplotypes in 30 families was measured by survival of skin grafts between selected paired family members. These families were genotyped for HL-A using 57 selected cytotoxic alloantisera defining HL-A 1–12 as well as other nondefined specificities. Mixed leukocyte reactions were also studied in this series and the correlations between the mixed leukocyte reactions with skin graft survival times, individual HL-A specificities, and the number of incompatible HL-A alleles are reported. Comments concerning the interpretation and quantitation of the mixed leukocyte reactions are discussed. The Rockefeller University Press 1971-02-28 /pmc/articles/PMC2138954/ /pubmed/4939150 Text en Copyright © 1971 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Seigler, H. F.
Ward, F. E.
Amos, D. B.
Phaup, M. B.
Stickel, D. L.
THE IMMUNOGENICITY OF HUMAN HL-A HAPLOTYPES AS MEASURED BY SKIN GRAFT SURVIVAL TIMES AND MIXED LEUKOCYTE REACTIONS
title THE IMMUNOGENICITY OF HUMAN HL-A HAPLOTYPES AS MEASURED BY SKIN GRAFT SURVIVAL TIMES AND MIXED LEUKOCYTE REACTIONS
title_full THE IMMUNOGENICITY OF HUMAN HL-A HAPLOTYPES AS MEASURED BY SKIN GRAFT SURVIVAL TIMES AND MIXED LEUKOCYTE REACTIONS
title_fullStr THE IMMUNOGENICITY OF HUMAN HL-A HAPLOTYPES AS MEASURED BY SKIN GRAFT SURVIVAL TIMES AND MIXED LEUKOCYTE REACTIONS
title_full_unstemmed THE IMMUNOGENICITY OF HUMAN HL-A HAPLOTYPES AS MEASURED BY SKIN GRAFT SURVIVAL TIMES AND MIXED LEUKOCYTE REACTIONS
title_short THE IMMUNOGENICITY OF HUMAN HL-A HAPLOTYPES AS MEASURED BY SKIN GRAFT SURVIVAL TIMES AND MIXED LEUKOCYTE REACTIONS
title_sort immunogenicity of human hl-a haplotypes as measured by skin graft survival times and mixed leukocyte reactions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138954/
https://www.ncbi.nlm.nih.gov/pubmed/4939150
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