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IGE AND IGGA ANTIBODY-MEDIATED RELEASE OF HISTAMINE FROM RAT PERITONEAL CELLS : I. OPTIMUM CONDITIONS FOR IN VITRO PREPARATION OF TARGET CELLS WITH ANTIBODY AND CHALLENGE WITH ANTIGEN
The optimum conditions for antigen-induced release of histamine in the rat IgE and IgGa antibody-mediated systems were studied in vitro. The IgE antibody-mediated reaction could be separated into two steps: preparation of target cells with antibody and challenge with antigen. The optimal conditions...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1971
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138970/ https://www.ncbi.nlm.nih.gov/pubmed/4100657 |
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author | Bach, Michael K. Bloch, Kurt J. Austen, K. Frank |
author_facet | Bach, Michael K. Bloch, Kurt J. Austen, K. Frank |
author_sort | Bach, Michael K. |
collection | PubMed |
description | The optimum conditions for antigen-induced release of histamine in the rat IgE and IgGa antibody-mediated systems were studied in vitro. The IgE antibody-mediated reaction could be separated into two steps: preparation of target cells with antibody and challenge with antigen. The optimal conditions for these two steps were distinctly different. Release of histamine by IgGa antibody and antigen could not be separated into two steps, and the optimal conditions for the total reaction were identical to those of the antigen challenge step of the IgE antibody-mediated system. |
format | Text |
id | pubmed-2138970 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1971 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21389702008-04-17 IGE AND IGGA ANTIBODY-MEDIATED RELEASE OF HISTAMINE FROM RAT PERITONEAL CELLS : I. OPTIMUM CONDITIONS FOR IN VITRO PREPARATION OF TARGET CELLS WITH ANTIBODY AND CHALLENGE WITH ANTIGEN Bach, Michael K. Bloch, Kurt J. Austen, K. Frank J Exp Med Article The optimum conditions for antigen-induced release of histamine in the rat IgE and IgGa antibody-mediated systems were studied in vitro. The IgE antibody-mediated reaction could be separated into two steps: preparation of target cells with antibody and challenge with antigen. The optimal conditions for these two steps were distinctly different. Release of histamine by IgGa antibody and antigen could not be separated into two steps, and the optimal conditions for the total reaction were identical to those of the antigen challenge step of the IgE antibody-mediated system. The Rockefeller University Press 1971-03-31 /pmc/articles/PMC2138970/ /pubmed/4100657 Text en Copyright © 1971 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Bach, Michael K. Bloch, Kurt J. Austen, K. Frank IGE AND IGGA ANTIBODY-MEDIATED RELEASE OF HISTAMINE FROM RAT PERITONEAL CELLS : I. OPTIMUM CONDITIONS FOR IN VITRO PREPARATION OF TARGET CELLS WITH ANTIBODY AND CHALLENGE WITH ANTIGEN |
title | IGE AND IGGA ANTIBODY-MEDIATED RELEASE OF HISTAMINE FROM RAT PERITONEAL CELLS : I. OPTIMUM CONDITIONS FOR IN VITRO PREPARATION OF TARGET CELLS WITH ANTIBODY AND CHALLENGE WITH ANTIGEN |
title_full | IGE AND IGGA ANTIBODY-MEDIATED RELEASE OF HISTAMINE FROM RAT PERITONEAL CELLS : I. OPTIMUM CONDITIONS FOR IN VITRO PREPARATION OF TARGET CELLS WITH ANTIBODY AND CHALLENGE WITH ANTIGEN |
title_fullStr | IGE AND IGGA ANTIBODY-MEDIATED RELEASE OF HISTAMINE FROM RAT PERITONEAL CELLS : I. OPTIMUM CONDITIONS FOR IN VITRO PREPARATION OF TARGET CELLS WITH ANTIBODY AND CHALLENGE WITH ANTIGEN |
title_full_unstemmed | IGE AND IGGA ANTIBODY-MEDIATED RELEASE OF HISTAMINE FROM RAT PERITONEAL CELLS : I. OPTIMUM CONDITIONS FOR IN VITRO PREPARATION OF TARGET CELLS WITH ANTIBODY AND CHALLENGE WITH ANTIGEN |
title_short | IGE AND IGGA ANTIBODY-MEDIATED RELEASE OF HISTAMINE FROM RAT PERITONEAL CELLS : I. OPTIMUM CONDITIONS FOR IN VITRO PREPARATION OF TARGET CELLS WITH ANTIBODY AND CHALLENGE WITH ANTIGEN |
title_sort | ige and igga antibody-mediated release of histamine from rat peritoneal cells : i. optimum conditions for in vitro preparation of target cells with antibody and challenge with antigen |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138970/ https://www.ncbi.nlm.nih.gov/pubmed/4100657 |
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