REQUIREMENT OF THYMUS (T) LYMPHOCYTES FOR RESISTANCE TO LISTERIOSIS

Spleen cells of mice infected with Listeria monocytogenes were adoptively transferred to normal mice. Such lymphocytes conferred resistance to a lethal challenge with Listeria. Hyperimmunization of the donor reduces the number of cells necessary to transfer effective immunity. Such spleen cells if t...

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Detalles Bibliográficos
Autores principales: Lane, F. C., Unanue, E. R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1972
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138983/
https://www.ncbi.nlm.nih.gov/pubmed/4623315
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author Lane, F. C.
Unanue, E. R.
author_facet Lane, F. C.
Unanue, E. R.
author_sort Lane, F. C.
collection PubMed
description Spleen cells of mice infected with Listeria monocytogenes were adoptively transferred to normal mice. Such lymphocytes conferred resistance to a lethal challenge with Listeria. Hyperimmunization of the donor reduces the number of cells necessary to transfer effective immunity. Such spleen cells if treated with anti-θ serum do not transfer resistance to Listeria. Hence, thymus (T) lymphocytes are involved in the resistance to infection with the facultative intracellular bacteria L. monocytogenes.
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spelling pubmed-21389832008-04-17 REQUIREMENT OF THYMUS (T) LYMPHOCYTES FOR RESISTANCE TO LISTERIOSIS Lane, F. C. Unanue, E. R. J Exp Med Article Spleen cells of mice infected with Listeria monocytogenes were adoptively transferred to normal mice. Such lymphocytes conferred resistance to a lethal challenge with Listeria. Hyperimmunization of the donor reduces the number of cells necessary to transfer effective immunity. Such spleen cells if treated with anti-θ serum do not transfer resistance to Listeria. Hence, thymus (T) lymphocytes are involved in the resistance to infection with the facultative intracellular bacteria L. monocytogenes. The Rockefeller University Press 1972-05-01 /pmc/articles/PMC2138983/ /pubmed/4623315 Text en Copyright © 1972 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Lane, F. C.
Unanue, E. R.
REQUIREMENT OF THYMUS (T) LYMPHOCYTES FOR RESISTANCE TO LISTERIOSIS
title REQUIREMENT OF THYMUS (T) LYMPHOCYTES FOR RESISTANCE TO LISTERIOSIS
title_full REQUIREMENT OF THYMUS (T) LYMPHOCYTES FOR RESISTANCE TO LISTERIOSIS
title_fullStr REQUIREMENT OF THYMUS (T) LYMPHOCYTES FOR RESISTANCE TO LISTERIOSIS
title_full_unstemmed REQUIREMENT OF THYMUS (T) LYMPHOCYTES FOR RESISTANCE TO LISTERIOSIS
title_short REQUIREMENT OF THYMUS (T) LYMPHOCYTES FOR RESISTANCE TO LISTERIOSIS
title_sort requirement of thymus (t) lymphocytes for resistance to listeriosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2138983/
https://www.ncbi.nlm.nih.gov/pubmed/4623315
work_keys_str_mv AT lanefc requirementofthymustlymphocytesforresistancetolisteriosis
AT unanueer requirementofthymustlymphocytesforresistancetolisteriosis

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