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LEUKEMIA EVOKED WITH 7, 8, 12-TRIMETHYLBENZ(A)ANTHRACENE IN RAT : I. CHANGES IN SPLEEN AND THYMUS
An early sign of erythroblastic leukemia in rat was nodule formation in the spleen. Hyperplastic foci of stem cells, indistinguishable histologically from leukemic stem cells, were found in the red pulp whereas the malpighian corpuscles were uninvolved. Anemia is a normal phenomenon in immature rats...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1971
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139007/ https://www.ncbi.nlm.nih.gov/pubmed/5286470 |