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THE INFLUENCE OF POSTNATAL DEVELOPMENT ON DRUG-INDUCED HEPATIC PORPHYRIA AND THE SYNTHESIS OF CYTOCHROME P-450 : A BIOCHEMICAL AND MORPHOLOGICAL STUDY
The mitochondrial enzyme δ-aminolevulinate synthetase (ALAS) controls the rate-limiting step in the synthesis of porphyrins and heme. An experimental form of hepatic porphyria can be readily elicited in laboratory animals, such as the rat, by drugs and foreign chemicals which are known to enhance th...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1971
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139010/ https://www.ncbi.nlm.nih.gov/pubmed/5112207 |