COMPLEMENT-DERIVED LEUKOTACTIC FACTORS IN PATHOLOGICAL FLUIDS

Leukotactic factors derived from the complement sequence consist of C5-related products, including the small cleavage product and the higher molecular weight complex (C567). A leukotactically active cleavage product (of low molecular weight) has also been described. The C5-related factors have been...

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Detalles Bibliográficos
Autor principal: Ward, Peter A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1971
Materias:
Mediation of Immunological Injury
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139064/
https://www.ncbi.nlm.nih.gov/pubmed/19867360
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author Ward, Peter A.
author_facet Ward, Peter A.
author_sort Ward, Peter A.
collection PubMed
description Leukotactic factors derived from the complement sequence consist of C5-related products, including the small cleavage product and the higher molecular weight complex (C567). A leukotactically active cleavage product (of low molecular weight) has also been described. The C5-related factors have been found in two conditions: soluble tissue extracts of immunologic vasculitis and in synovial fluids from patients with rheumatoid arthritis. The C3-related product has been found in synovial fluids from patients with inflammatory, nonrheumatoid arthritis and in extracts of experimentally infarcted myocardium. The presence of these factors may be causally related to the acute inflammatory nature of the cellular exudates.
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spelling pubmed-21390642008-04-17 COMPLEMENT-DERIVED LEUKOTACTIC FACTORS IN PATHOLOGICAL FLUIDS Ward, Peter A. J Exp Med Mediation of Immunological Injury Leukotactic factors derived from the complement sequence consist of C5-related products, including the small cleavage product and the higher molecular weight complex (C567). A leukotactically active cleavage product (of low molecular weight) has also been described. The C5-related factors have been found in two conditions: soluble tissue extracts of immunologic vasculitis and in synovial fluids from patients with rheumatoid arthritis. The C3-related product has been found in synovial fluids from patients with inflammatory, nonrheumatoid arthritis and in extracts of experimentally infarcted myocardium. The presence of these factors may be causally related to the acute inflammatory nature of the cellular exudates. The Rockefeller University Press 1971-09-01 /pmc/articles/PMC2139064/ /pubmed/19867360 Text en Copyright © 1971 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Mediation of Immunological Injury
Ward, Peter A.
COMPLEMENT-DERIVED LEUKOTACTIC FACTORS IN PATHOLOGICAL FLUIDS
title COMPLEMENT-DERIVED LEUKOTACTIC FACTORS IN PATHOLOGICAL FLUIDS
title_full COMPLEMENT-DERIVED LEUKOTACTIC FACTORS IN PATHOLOGICAL FLUIDS
title_fullStr COMPLEMENT-DERIVED LEUKOTACTIC FACTORS IN PATHOLOGICAL FLUIDS
title_full_unstemmed COMPLEMENT-DERIVED LEUKOTACTIC FACTORS IN PATHOLOGICAL FLUIDS
title_short COMPLEMENT-DERIVED LEUKOTACTIC FACTORS IN PATHOLOGICAL FLUIDS
title_sort complement-derived leukotactic factors in pathological fluids
topic Mediation of Immunological Injury
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139064/
https://www.ncbi.nlm.nih.gov/pubmed/19867360
work_keys_str_mv AT wardpetera complementderivedleukotacticfactorsinpathologicalfluids

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