CAPSULATION OF PNEUMOCOCCUS WITH SOLUBLE CELL WALL-LIKE POLYSACCHARIDE : II. NONIDENTITY OF CELL WALL AND SOLUBLE CELL WALL-LIKE POLYSACCHARIDES DERIVED FROM THE SAME AND FROM DIFFERENT PNEUMOCOCCAL STRAINS

Methods are described for the separation of the C or cell wall polysaccharide from the C(s) or soluble C-like capsular polysaccharide of C(s) pneumococcal strains. Immunologic analysis has shown that both the C and C(s) polysaccharides of a variety of pneumococcal strains are heterogeneous and that...

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Detalles Bibliográficos
Autores principales: Schiffman, Gerald, Bornstein, Donald L., Austrian, Robert
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1971
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139069/
https://www.ncbi.nlm.nih.gov/pubmed/15776564
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author Schiffman, Gerald
Bornstein, Donald L.
Austrian, Robert
author_facet Schiffman, Gerald
Bornstein, Donald L.
Austrian, Robert
author_sort Schiffman, Gerald
collection PubMed
description Methods are described for the separation of the C or cell wall polysaccharide from the C(s) or soluble C-like capsular polysaccharide of C(s) pneumococcal strains. Immunologic analysis has shown that both the C and C(s) polysaccharides of a variety of pneumococcal strains are heterogeneous and that the dissimilarities appear to reside in the mucopeptide portion of the molecule or in the region of its attachment to the teichoic acid moiety of the molecule rather than in the teichoic acid fraction. Differences of the type described have been observed in the C polysaccharides of wild-type capsulated strains of several types, in those of independently isolated noncapsulated variants derived from a single strain of a given capsular type, and in the C and C(s) polysaccharides of spontaneous mutant or transformed strains of pneumococci producing capsules of C(s) polysaccharide.
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spelling pubmed-21390692008-04-17 CAPSULATION OF PNEUMOCOCCUS WITH SOLUBLE CELL WALL-LIKE POLYSACCHARIDE : II. NONIDENTITY OF CELL WALL AND SOLUBLE CELL WALL-LIKE POLYSACCHARIDES DERIVED FROM THE SAME AND FROM DIFFERENT PNEUMOCOCCAL STRAINS Schiffman, Gerald Bornstein, Donald L. Austrian, Robert J Exp Med Article Methods are described for the separation of the C or cell wall polysaccharide from the C(s) or soluble C-like capsular polysaccharide of C(s) pneumococcal strains. Immunologic analysis has shown that both the C and C(s) polysaccharides of a variety of pneumococcal strains are heterogeneous and that the dissimilarities appear to reside in the mucopeptide portion of the molecule or in the region of its attachment to the teichoic acid moiety of the molecule rather than in the teichoic acid fraction. Differences of the type described have been observed in the C polysaccharides of wild-type capsulated strains of several types, in those of independently isolated noncapsulated variants derived from a single strain of a given capsular type, and in the C and C(s) polysaccharides of spontaneous mutant or transformed strains of pneumococci producing capsules of C(s) polysaccharide. The Rockefeller University Press 1971-09-01 /pmc/articles/PMC2139069/ /pubmed/15776564 Text en Copyright © 1971 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Schiffman, Gerald
Bornstein, Donald L.
Austrian, Robert
CAPSULATION OF PNEUMOCOCCUS WITH SOLUBLE CELL WALL-LIKE POLYSACCHARIDE : II. NONIDENTITY OF CELL WALL AND SOLUBLE CELL WALL-LIKE POLYSACCHARIDES DERIVED FROM THE SAME AND FROM DIFFERENT PNEUMOCOCCAL STRAINS
title CAPSULATION OF PNEUMOCOCCUS WITH SOLUBLE CELL WALL-LIKE POLYSACCHARIDE : II. NONIDENTITY OF CELL WALL AND SOLUBLE CELL WALL-LIKE POLYSACCHARIDES DERIVED FROM THE SAME AND FROM DIFFERENT PNEUMOCOCCAL STRAINS
title_full CAPSULATION OF PNEUMOCOCCUS WITH SOLUBLE CELL WALL-LIKE POLYSACCHARIDE : II. NONIDENTITY OF CELL WALL AND SOLUBLE CELL WALL-LIKE POLYSACCHARIDES DERIVED FROM THE SAME AND FROM DIFFERENT PNEUMOCOCCAL STRAINS
title_fullStr CAPSULATION OF PNEUMOCOCCUS WITH SOLUBLE CELL WALL-LIKE POLYSACCHARIDE : II. NONIDENTITY OF CELL WALL AND SOLUBLE CELL WALL-LIKE POLYSACCHARIDES DERIVED FROM THE SAME AND FROM DIFFERENT PNEUMOCOCCAL STRAINS
title_full_unstemmed CAPSULATION OF PNEUMOCOCCUS WITH SOLUBLE CELL WALL-LIKE POLYSACCHARIDE : II. NONIDENTITY OF CELL WALL AND SOLUBLE CELL WALL-LIKE POLYSACCHARIDES DERIVED FROM THE SAME AND FROM DIFFERENT PNEUMOCOCCAL STRAINS
title_short CAPSULATION OF PNEUMOCOCCUS WITH SOLUBLE CELL WALL-LIKE POLYSACCHARIDE : II. NONIDENTITY OF CELL WALL AND SOLUBLE CELL WALL-LIKE POLYSACCHARIDES DERIVED FROM THE SAME AND FROM DIFFERENT PNEUMOCOCCAL STRAINS
title_sort capsulation of pneumococcus with soluble cell wall-like polysaccharide : ii. nonidentity of cell wall and soluble cell wall-like polysaccharides derived from the same and from different pneumococcal strains
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139069/
https://www.ncbi.nlm.nih.gov/pubmed/15776564
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