THE PROLIFERATION OF PLASMA CELLS FROM MOUSE BONE MARROW IN VITRO : I. THE ROLE OF THYMUS

An in vitro proliferative system for immunoglobulin-G-forming plasma cells from the bone marrow of mice was established by the addition of antigenic protein and thymic cells or their homogenate to bone marrow cultures. The promoting activity of the thymus on plasma cells was independent from mouse s...

Descripción completa

Detalles Bibliográficos
Autor principal: Nakamura, Kunie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1972
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139139/
https://www.ncbi.nlm.nih.gov/pubmed/4621661
_version_ 1782143726520369152
author Nakamura, Kunie
author_facet Nakamura, Kunie
author_sort Nakamura, Kunie
collection PubMed
description An in vitro proliferative system for immunoglobulin-G-forming plasma cells from the bone marrow of mice was established by the addition of antigenic protein and thymic cells or their homogenate to bone marrow cultures. The promoting activity of the thymus on plasma cells was independent from mouse strain, but it differed in strength with the variations of donor strains. Synthesis of immunoglobulin-G in proliferating plasma cells and its antibody reactivity against the administered antigen were demonstrated by immunocytological analyses.
format Text
id pubmed-2139139
institution National Center for Biotechnology Information
language English
publishDate 1972
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21391392008-04-17 THE PROLIFERATION OF PLASMA CELLS FROM MOUSE BONE MARROW IN VITRO : I. THE ROLE OF THYMUS Nakamura, Kunie J Exp Med Article An in vitro proliferative system for immunoglobulin-G-forming plasma cells from the bone marrow of mice was established by the addition of antigenic protein and thymic cells or their homogenate to bone marrow cultures. The promoting activity of the thymus on plasma cells was independent from mouse strain, but it differed in strength with the variations of donor strains. Synthesis of immunoglobulin-G in proliferating plasma cells and its antibody reactivity against the administered antigen were demonstrated by immunocytological analyses. The Rockefeller University Press 1972-02-29 /pmc/articles/PMC2139139/ /pubmed/4621661 Text en Copyright © 1972 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Nakamura, Kunie
THE PROLIFERATION OF PLASMA CELLS FROM MOUSE BONE MARROW IN VITRO : I. THE ROLE OF THYMUS
title THE PROLIFERATION OF PLASMA CELLS FROM MOUSE BONE MARROW IN VITRO : I. THE ROLE OF THYMUS
title_full THE PROLIFERATION OF PLASMA CELLS FROM MOUSE BONE MARROW IN VITRO : I. THE ROLE OF THYMUS
title_fullStr THE PROLIFERATION OF PLASMA CELLS FROM MOUSE BONE MARROW IN VITRO : I. THE ROLE OF THYMUS
title_full_unstemmed THE PROLIFERATION OF PLASMA CELLS FROM MOUSE BONE MARROW IN VITRO : I. THE ROLE OF THYMUS
title_short THE PROLIFERATION OF PLASMA CELLS FROM MOUSE BONE MARROW IN VITRO : I. THE ROLE OF THYMUS
title_sort proliferation of plasma cells from mouse bone marrow in vitro : i. the role of thymus
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139139/
https://www.ncbi.nlm.nih.gov/pubmed/4621661
work_keys_str_mv AT nakamurakunie theproliferationofplasmacellsfrommousebonemarrowinvitroitheroleofthymus
AT nakamurakunie proliferationofplasmacellsfrommousebonemarrowinvitroitheroleofthymus

Ejemplares similares