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LYMPHOID CELLS IN DELAYED HYPERSENSITIVITY : III. THE INFLUENCE OF X-IRRADIATION ON PASSIVE TRANSFER AND ON IN VITRO PRODUCTION OF SOLUBLE MEDIATORS
X-irradiation up to 480 R does not inhibit either adoptive transfer of delayed hypersensitivity or production in vitro of soluble mediators, such as migration-inhibitory factor (MIF). Above that dosage and as high as 3000 R, adoptive transfer is inhibited, but production of MIF is not. An increase i...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1972
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139154/ https://www.ncbi.nlm.nih.gov/pubmed/5018056 |
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author | Salvin, S. B. Nishio, J. |
author_facet | Salvin, S. B. Nishio, J. |
author_sort | Salvin, S. B. |
collection | PubMed |
description | X-irradiation up to 480 R does not inhibit either adoptive transfer of delayed hypersensitivity or production in vitro of soluble mediators, such as migration-inhibitory factor (MIF). Above that dosage and as high as 3000 R, adoptive transfer is inhibited, but production of MIF is not. An increase in skin response occurred when 24–48 hr were allowed to elapse after intravenous transfer and before skin testing. Treatment of recipients with colchicine at the time of adoptive transfer inhibited the development of a skin reaction to specific antigen. |
format | Text |
id | pubmed-2139154 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1972 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21391542008-04-17 LYMPHOID CELLS IN DELAYED HYPERSENSITIVITY : III. THE INFLUENCE OF X-IRRADIATION ON PASSIVE TRANSFER AND ON IN VITRO PRODUCTION OF SOLUBLE MEDIATORS Salvin, S. B. Nishio, J. J Exp Med Article X-irradiation up to 480 R does not inhibit either adoptive transfer of delayed hypersensitivity or production in vitro of soluble mediators, such as migration-inhibitory factor (MIF). Above that dosage and as high as 3000 R, adoptive transfer is inhibited, but production of MIF is not. An increase in skin response occurred when 24–48 hr were allowed to elapse after intravenous transfer and before skin testing. Treatment of recipients with colchicine at the time of adoptive transfer inhibited the development of a skin reaction to specific antigen. The Rockefeller University Press 1972-03-31 /pmc/articles/PMC2139154/ /pubmed/5018056 Text en Copyright © 1972 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Salvin, S. B. Nishio, J. LYMPHOID CELLS IN DELAYED HYPERSENSITIVITY : III. THE INFLUENCE OF X-IRRADIATION ON PASSIVE TRANSFER AND ON IN VITRO PRODUCTION OF SOLUBLE MEDIATORS |
title | LYMPHOID CELLS IN DELAYED HYPERSENSITIVITY : III. THE INFLUENCE OF X-IRRADIATION ON PASSIVE TRANSFER AND ON IN VITRO PRODUCTION OF SOLUBLE MEDIATORS |
title_full | LYMPHOID CELLS IN DELAYED HYPERSENSITIVITY : III. THE INFLUENCE OF X-IRRADIATION ON PASSIVE TRANSFER AND ON IN VITRO PRODUCTION OF SOLUBLE MEDIATORS |
title_fullStr | LYMPHOID CELLS IN DELAYED HYPERSENSITIVITY : III. THE INFLUENCE OF X-IRRADIATION ON PASSIVE TRANSFER AND ON IN VITRO PRODUCTION OF SOLUBLE MEDIATORS |
title_full_unstemmed | LYMPHOID CELLS IN DELAYED HYPERSENSITIVITY : III. THE INFLUENCE OF X-IRRADIATION ON PASSIVE TRANSFER AND ON IN VITRO PRODUCTION OF SOLUBLE MEDIATORS |
title_short | LYMPHOID CELLS IN DELAYED HYPERSENSITIVITY : III. THE INFLUENCE OF X-IRRADIATION ON PASSIVE TRANSFER AND ON IN VITRO PRODUCTION OF SOLUBLE MEDIATORS |
title_sort | lymphoid cells in delayed hypersensitivity : iii. the influence of x-irradiation on passive transfer and on in vitro production of soluble mediators |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139154/ https://www.ncbi.nlm.nih.gov/pubmed/5018056 |
work_keys_str_mv | AT salvinsb lymphoidcellsindelayedhypersensitivityiiitheinfluenceofxirradiationonpassivetransferandoninvitroproductionofsolublemediators AT nishioj lymphoidcellsindelayedhypersensitivityiiitheinfluenceofxirradiationonpassivetransferandoninvitroproductionofsolublemediators |