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INTERACTION OF AGGREGATED γ-GLOBULIN WITH B LYMPHOCYTES
Specific binding of aggregated γ-globulin to a subpopulation of lymphocytes was demonstrated. This subpopulation was identified as the Ig-staining or B lymphocytes. The binding was irreversible and independent of complement, pH, temperature, protein content of the medium, and divalent cations. Aggre...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1972
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139185/ https://www.ncbi.nlm.nih.gov/pubmed/4113510 |
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author | Dickler, H. B. Kunkel, H. G. |
author_facet | Dickler, H. B. Kunkel, H. G. |
author_sort | Dickler, H. B. |
collection | PubMed |
description | Specific binding of aggregated γ-globulin to a subpopulation of lymphocytes was demonstrated. This subpopulation was identified as the Ig-staining or B lymphocytes. The binding was irreversible and independent of complement, pH, temperature, protein content of the medium, and divalent cations. Aggregates of large size were needed for optimal visualization. Evidence was obtained that the site on the lymphocyte membrane responsible for binding aggregates was distinct from surface Ig. |
format | Text |
id | pubmed-2139185 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1972 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21391852008-04-17 INTERACTION OF AGGREGATED γ-GLOBULIN WITH B LYMPHOCYTES Dickler, H. B. Kunkel, H. G. J Exp Med Brief Definitive Reports Specific binding of aggregated γ-globulin to a subpopulation of lymphocytes was demonstrated. This subpopulation was identified as the Ig-staining or B lymphocytes. The binding was irreversible and independent of complement, pH, temperature, protein content of the medium, and divalent cations. Aggregates of large size were needed for optimal visualization. Evidence was obtained that the site on the lymphocyte membrane responsible for binding aggregates was distinct from surface Ig. The Rockefeller University Press 1972-07-01 /pmc/articles/PMC2139185/ /pubmed/4113510 Text en Copyright © 1972 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Brief Definitive Reports Dickler, H. B. Kunkel, H. G. INTERACTION OF AGGREGATED γ-GLOBULIN WITH B LYMPHOCYTES |
title | INTERACTION OF AGGREGATED γ-GLOBULIN WITH B LYMPHOCYTES |
title_full | INTERACTION OF AGGREGATED γ-GLOBULIN WITH B LYMPHOCYTES |
title_fullStr | INTERACTION OF AGGREGATED γ-GLOBULIN WITH B LYMPHOCYTES |
title_full_unstemmed | INTERACTION OF AGGREGATED γ-GLOBULIN WITH B LYMPHOCYTES |
title_short | INTERACTION OF AGGREGATED γ-GLOBULIN WITH B LYMPHOCYTES |
title_sort | interaction of aggregated γ-globulin with b lymphocytes |
topic | Brief Definitive Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139185/ https://www.ncbi.nlm.nih.gov/pubmed/4113510 |
work_keys_str_mv | AT dicklerhb interactionofaggregatedgglobulinwithblymphocytes AT kunkelhg interactionofaggregatedgglobulinwithblymphocytes |