GENETIC FACTORS INFLUENCING C-TYPE RNA VIRUS INDUCTION

Genetic factors were studied which affect the inducibility of C-type RNA viruses from embyro cultures of mouse strains with high and low incidence of spontaneous leukemia. Virus was inducible by chemical treatment from secondary embryo cultures of several inbred strains. Both virus inducibility and...

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Detalles Bibliográficos
Autores principales: Stephenson, John R., Aaronson, Stuart A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1972
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139189/
https://www.ncbi.nlm.nih.gov/pubmed/4113509
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author Stephenson, John R.
Aaronson, Stuart A.
author_facet Stephenson, John R.
Aaronson, Stuart A.
author_sort Stephenson, John R.
collection PubMed
description Genetic factors were studied which affect the inducibility of C-type RNA viruses from embyro cultures of mouse strains with high and low incidence of spontaneous leukemia. Virus was inducible by chemical treatment from secondary embryo cultures of several inbred strains. Both virus inducibility and the capacity of the virus to persist in cells from which it was activated were found to be inherited as dominant genetic characteristics. The results show that the factors controlling virus activation and persistence in culture also play an important role in spontaneous virus expression in the animal.
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spelling pubmed-21391892008-04-17 GENETIC FACTORS INFLUENCING C-TYPE RNA VIRUS INDUCTION Stephenson, John R. Aaronson, Stuart A. J Exp Med Article Genetic factors were studied which affect the inducibility of C-type RNA viruses from embyro cultures of mouse strains with high and low incidence of spontaneous leukemia. Virus was inducible by chemical treatment from secondary embryo cultures of several inbred strains. Both virus inducibility and the capacity of the virus to persist in cells from which it was activated were found to be inherited as dominant genetic characteristics. The results show that the factors controlling virus activation and persistence in culture also play an important role in spontaneous virus expression in the animal. The Rockefeller University Press 1972-07-01 /pmc/articles/PMC2139189/ /pubmed/4113509 Text en Copyright © 1972 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Stephenson, John R.
Aaronson, Stuart A.
GENETIC FACTORS INFLUENCING C-TYPE RNA VIRUS INDUCTION
title GENETIC FACTORS INFLUENCING C-TYPE RNA VIRUS INDUCTION
title_full GENETIC FACTORS INFLUENCING C-TYPE RNA VIRUS INDUCTION
title_fullStr GENETIC FACTORS INFLUENCING C-TYPE RNA VIRUS INDUCTION
title_full_unstemmed GENETIC FACTORS INFLUENCING C-TYPE RNA VIRUS INDUCTION
title_short GENETIC FACTORS INFLUENCING C-TYPE RNA VIRUS INDUCTION
title_sort genetic factors influencing c-type rna virus induction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139189/
https://www.ncbi.nlm.nih.gov/pubmed/4113509
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AT aaronsonstuarta geneticfactorsinfluencingctypernavirusinduction

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