THE RELATIONSHIP BETWEEN β(2)-MICROGLOBULIN AND IMMUNOGLOBULIN IN CULTURED HUMAN LYMPHOID CELL LINES

β(2)-microglobulin was detected on the cell surface and in the medium of human lymphoid cells established in long-term culture. The secretion of β(2)-microglobulin was relatively uniform when different cell lines were compared, whereas IgG production varied widely. κ- and µ-membrane antigens were mo...

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Detalles Bibliográficos
Autores principales: Hütteroth, T. H., Cleve, H., Litwin, S. D., Poulik, M. D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1973
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139389/
https://www.ncbi.nlm.nih.gov/pubmed/4120289
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author Hütteroth, T. H.
Cleve, H.
Litwin, S. D.
Poulik, M. D.
author_facet Hütteroth, T. H.
Cleve, H.
Litwin, S. D.
Poulik, M. D.
author_sort Hütteroth, T. H.
collection PubMed
description β(2)-microglobulin was detected on the cell surface and in the medium of human lymphoid cells established in long-term culture. The secretion of β(2)-microglobulin was relatively uniform when different cell lines were compared, whereas IgG production varied widely. κ- and µ-membrane antigens were modulated by specific antibody; β(2)-microglobulin was not modulated. Anti-κ and anti-µ antisera had no effect on the expression of membrane β(2)-microglobulin, nor had anti-β(2)-microglobulin antiserum any effect on the expression of κ- and µ-membrane antigens.
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spelling pubmed-21393892008-04-17 THE RELATIONSHIP BETWEEN β(2)-MICROGLOBULIN AND IMMUNOGLOBULIN IN CULTURED HUMAN LYMPHOID CELL LINES Hütteroth, T. H. Cleve, H. Litwin, S. D. Poulik, M. D. J Exp Med Brief Definitive Reports β(2)-microglobulin was detected on the cell surface and in the medium of human lymphoid cells established in long-term culture. The secretion of β(2)-microglobulin was relatively uniform when different cell lines were compared, whereas IgG production varied widely. κ- and µ-membrane antigens were modulated by specific antibody; β(2)-microglobulin was not modulated. Anti-κ and anti-µ antisera had no effect on the expression of membrane β(2)-microglobulin, nor had anti-β(2)-microglobulin antiserum any effect on the expression of κ- and µ-membrane antigens. The Rockefeller University Press 1973-02-28 /pmc/articles/PMC2139389/ /pubmed/4120289 Text en Copyright © 1973 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Brief Definitive Reports
Hütteroth, T. H.
Cleve, H.
Litwin, S. D.
Poulik, M. D.
THE RELATIONSHIP BETWEEN β(2)-MICROGLOBULIN AND IMMUNOGLOBULIN IN CULTURED HUMAN LYMPHOID CELL LINES
title THE RELATIONSHIP BETWEEN β(2)-MICROGLOBULIN AND IMMUNOGLOBULIN IN CULTURED HUMAN LYMPHOID CELL LINES
title_full THE RELATIONSHIP BETWEEN β(2)-MICROGLOBULIN AND IMMUNOGLOBULIN IN CULTURED HUMAN LYMPHOID CELL LINES
title_fullStr THE RELATIONSHIP BETWEEN β(2)-MICROGLOBULIN AND IMMUNOGLOBULIN IN CULTURED HUMAN LYMPHOID CELL LINES
title_full_unstemmed THE RELATIONSHIP BETWEEN β(2)-MICROGLOBULIN AND IMMUNOGLOBULIN IN CULTURED HUMAN LYMPHOID CELL LINES
title_short THE RELATIONSHIP BETWEEN β(2)-MICROGLOBULIN AND IMMUNOGLOBULIN IN CULTURED HUMAN LYMPHOID CELL LINES
title_sort relationship between β(2)-microglobulin and immunoglobulin in cultured human lymphoid cell lines
topic Brief Definitive Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139389/
https://www.ncbi.nlm.nih.gov/pubmed/4120289
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