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INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION

Chymotrypsin- and Pronase-treated human erythrocytes were refractory to invasion by P. knowlesi merozoites; invasion was not inhibited by trypsin or neurammidase treatment. These data implicate a surface protein other than sialoglycoprotein as the receptor site for merozoites. Invasion of rhesus ery...

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Detalles Bibliográficos
Autores principales: Miller, Louis H., Dvorak, James A., Shiroishi, Tsugiye, Durocher, John R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1973
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139457/
https://www.ncbi.nlm.nih.gov/pubmed/4202732
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author Miller, Louis H.
Dvorak, James A.
Shiroishi, Tsugiye
Durocher, John R.
author_facet Miller, Louis H.
Dvorak, James A.
Shiroishi, Tsugiye
Durocher, John R.
author_sort Miller, Louis H.
collection PubMed
description Chymotrypsin- and Pronase-treated human erythrocytes were refractory to invasion by P. knowlesi merozoites; invasion was not inhibited by trypsin or neurammidase treatment. These data implicate a surface protein other than sialoglycoprotein as the receptor site for merozoites. Invasion of rhesus erythrocytes was unaffected by pretreatment with these enzymes. Differences in membrane structure of erythrocytes from various species may explain the absence of an enzyme effect on rhesus erythrocytes.
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spelling pubmed-21394572008-04-17 INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION Miller, Louis H. Dvorak, James A. Shiroishi, Tsugiye Durocher, John R. J Exp Med Brief Definitive Reports Chymotrypsin- and Pronase-treated human erythrocytes were refractory to invasion by P. knowlesi merozoites; invasion was not inhibited by trypsin or neurammidase treatment. These data implicate a surface protein other than sialoglycoprotein as the receptor site for merozoites. Invasion of rhesus erythrocytes was unaffected by pretreatment with these enzymes. Differences in membrane structure of erythrocytes from various species may explain the absence of an enzyme effect on rhesus erythrocytes. The Rockefeller University Press 1973-11-30 /pmc/articles/PMC2139457/ /pubmed/4202732 Text en Copyright © 1973 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Brief Definitive Reports
Miller, Louis H.
Dvorak, James A.
Shiroishi, Tsugiye
Durocher, John R.
INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION
title INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION
title_full INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION
title_fullStr INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION
title_full_unstemmed INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION
title_short INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION
title_sort influence of erythrocyte membrane components on malaria merozoite invasion
topic Brief Definitive Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139457/
https://www.ncbi.nlm.nih.gov/pubmed/4202732
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