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INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION
Chymotrypsin- and Pronase-treated human erythrocytes were refractory to invasion by P. knowlesi merozoites; invasion was not inhibited by trypsin or neurammidase treatment. These data implicate a surface protein other than sialoglycoprotein as the receptor site for merozoites. Invasion of rhesus ery...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1973
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139457/ https://www.ncbi.nlm.nih.gov/pubmed/4202732 |
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author | Miller, Louis H. Dvorak, James A. Shiroishi, Tsugiye Durocher, John R. |
author_facet | Miller, Louis H. Dvorak, James A. Shiroishi, Tsugiye Durocher, John R. |
author_sort | Miller, Louis H. |
collection | PubMed |
description | Chymotrypsin- and Pronase-treated human erythrocytes were refractory to invasion by P. knowlesi merozoites; invasion was not inhibited by trypsin or neurammidase treatment. These data implicate a surface protein other than sialoglycoprotein as the receptor site for merozoites. Invasion of rhesus erythrocytes was unaffected by pretreatment with these enzymes. Differences in membrane structure of erythrocytes from various species may explain the absence of an enzyme effect on rhesus erythrocytes. |
format | Text |
id | pubmed-2139457 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1973 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21394572008-04-17 INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION Miller, Louis H. Dvorak, James A. Shiroishi, Tsugiye Durocher, John R. J Exp Med Brief Definitive Reports Chymotrypsin- and Pronase-treated human erythrocytes were refractory to invasion by P. knowlesi merozoites; invasion was not inhibited by trypsin or neurammidase treatment. These data implicate a surface protein other than sialoglycoprotein as the receptor site for merozoites. Invasion of rhesus erythrocytes was unaffected by pretreatment with these enzymes. Differences in membrane structure of erythrocytes from various species may explain the absence of an enzyme effect on rhesus erythrocytes. The Rockefeller University Press 1973-11-30 /pmc/articles/PMC2139457/ /pubmed/4202732 Text en Copyright © 1973 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Brief Definitive Reports Miller, Louis H. Dvorak, James A. Shiroishi, Tsugiye Durocher, John R. INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION |
title | INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION |
title_full | INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION |
title_fullStr | INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION |
title_full_unstemmed | INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION |
title_short | INFLUENCE OF ERYTHROCYTE MEMBRANE COMPONENTS ON MALARIA MEROZOITE INVASION |
title_sort | influence of erythrocyte membrane components on malaria merozoite invasion |
topic | Brief Definitive Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139457/ https://www.ncbi.nlm.nih.gov/pubmed/4202732 |
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