PRODUCTION OF TL ANTIBODY BY MICE IMMUNIZED WITH TL(-) CELL POPULATIONS : A POSSIBLE ASSAY FOR THYMIC HORMONE

TL(-) mice make TL antibody when immunized with spleen or bone marrow cells from TL(+) donors, despite the fact that these cells do not express TL antigen. This has been shown to depend on maturation of TL(-) precursors, contained in the inoculum, into TL(+) cells under influence of the recipient�...

Descripción completa

Detalles Bibliográficos
Autores principales: Komuro, Katsutoshi, Boyse, Edward A., Old, Lloyd J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1973
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139483/
https://www.ncbi.nlm.nih.gov/pubmed/4685707
Descripción
Sumario:TL(-) mice make TL antibody when immunized with spleen or bone marrow cells from TL(+) donors, despite the fact that these cells do not express TL antigen. This has been shown to depend on maturation of TL(-) precursors, contained in the inoculum, into TL(+) cells under influence of the recipient's thymus; the differentiated TL(+) cells then evoke production of TL antibody.

Ejemplares similares