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PROPERDIN FACTOR D: CHARACTERIZATION OF ITS ACTIVE SITE AND ISOLATION OF THE PRECURSOR FORM
The activity of properdin factor D was measured by the generation of the hemolytically active cellular intermediate, EAC43B(D), bearing the C3b-dependent alternate pathway C3 convertase. Treatment of factor D with DFP prevented formation of EAC43B(D); thus, a serine esterase is essential for the gen...
Autores principales: | Fearon, Douglas T., Austen, K. Frank, Ruddy, Shaun |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1974
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139519/ https://www.ncbi.nlm.nih.gov/pubmed/4855753 |
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