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NEW, THIRD CLASS OF AMYLOID FIBRIL PROTEIN

An unusual protein AR was isolated from the amyloid fibril preparation derived from a patient with primary amyloidosis. Protein AR was unique in its antigenicity, and revealed no structural identity with any known amyloid proteins or with immunoglobulin chains or fragments. Thus a new third class of...

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Detalles Bibliográficos
Autores principales: Husby, G., Natvig, J. B., Sletten, K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1974
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139555/
https://www.ncbi.nlm.nih.gov/pubmed/4204730
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author Husby, G.
Natvig, J. B.
Sletten, K.
author_facet Husby, G.
Natvig, J. B.
Sletten, K.
author_sort Husby, G.
collection PubMed
description An unusual protein AR was isolated from the amyloid fibril preparation derived from a patient with primary amyloidosis. Protein AR was unique in its antigenicity, and revealed no structural identity with any known amyloid proteins or with immunoglobulin chains or fragments. Thus a new third class of amyloid fibril proteins besides the immunoglobulin light-chain variable region fragments and the nonimmunoglobulin protein AS, has been characterized. A component antigenically related to protein AR was found in the serum of the patient.
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spelling pubmed-21395552008-04-17 NEW, THIRD CLASS OF AMYLOID FIBRIL PROTEIN Husby, G. Natvig, J. B. Sletten, K. J Exp Med Brief Definitive Reports An unusual protein AR was isolated from the amyloid fibril preparation derived from a patient with primary amyloidosis. Protein AR was unique in its antigenicity, and revealed no structural identity with any known amyloid proteins or with immunoglobulin chains or fragments. Thus a new third class of amyloid fibril proteins besides the immunoglobulin light-chain variable region fragments and the nonimmunoglobulin protein AS, has been characterized. A component antigenically related to protein AR was found in the serum of the patient. The Rockefeller University Press 1974-03-01 /pmc/articles/PMC2139555/ /pubmed/4204730 Text en Copyright © 1974 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Brief Definitive Reports
Husby, G.
Natvig, J. B.
Sletten, K.
NEW, THIRD CLASS OF AMYLOID FIBRIL PROTEIN
title NEW, THIRD CLASS OF AMYLOID FIBRIL PROTEIN
title_full NEW, THIRD CLASS OF AMYLOID FIBRIL PROTEIN
title_fullStr NEW, THIRD CLASS OF AMYLOID FIBRIL PROTEIN
title_full_unstemmed NEW, THIRD CLASS OF AMYLOID FIBRIL PROTEIN
title_short NEW, THIRD CLASS OF AMYLOID FIBRIL PROTEIN
title_sort new, third class of amyloid fibril protein
topic Brief Definitive Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139555/
https://www.ncbi.nlm.nih.gov/pubmed/4204730
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