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GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO : II. EFFECT OF REPEATED EXPOSURE TO ALLOANTIGENS ON THE CYTOTOXIC ACTIVITY OF LONG-TERM MIXED LEUKOCYTE CULTURES

Mouse cytotoxic T lymphocytes (CTL) were generated in unidirectional mixed leukocyte cultures (MLC) using normal C57BL/6 spleen cells as responding cells and irradiated DBA/2 spleen cells as stimulating cells. Cytotoxicity was assayed on (51)Cr-labeled P-815 (DBA/2) target cells, and the relative fr...

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Detalles Bibliográficos
Autores principales:	MacDonald, H. Robson, Engers, Howard D., Cerottini, Jean-Charles, Brunner, K. Theodor
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1974
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139618/ https://www.ncbi.nlm.nih.gov/pubmed/4278109

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