CELL-BOUND RECEPTORS FOR ALLOANTIGENS ON NORMAL LYMPHOCYTES : II. ANTIALLOANTIBODY SERUM CONTAINS SPECIFIC FACTORS REACTING WITH RELEVANT IMMUNOCOMPETENT T LYMPHOCYTES

The rat popliteal node graft-vs.-host assay was shown to depend on the presence of parental T cells in the inoculum. Antialloantisera raised in F(1) hybrid rats against alloantibodies of one parent directed at transplantation antigens of the other parent displayed some or all of the following specif...

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Detalles Bibliográficos
Autores principales: Binz, Hans, Lindenmann, Jean, Wigzell, Hans
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1974
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139621/
https://www.ncbi.nlm.nih.gov/pubmed/4153293
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author Binz, Hans
Lindenmann, Jean
Wigzell, Hans
author_facet Binz, Hans
Lindenmann, Jean
Wigzell, Hans
author_sort Binz, Hans
collection PubMed
description The rat popliteal node graft-vs.-host assay was shown to depend on the presence of parental T cells in the inoculum. Antialloantisera raised in F(1) hybrid rats against alloantibodies of one parent directed at transplantation antigens of the other parent displayed some or all of the following specific effects on parental T cells: They inhibited local GvH by purified T-cell suspensions; they blocked the capacity of GvH-reactive cells to adsorb onto fibroblast monolayers of the relevant genotype; together with complement, they killed GvH-reactive cells.
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spelling pubmed-21396212008-04-17 CELL-BOUND RECEPTORS FOR ALLOANTIGENS ON NORMAL LYMPHOCYTES : II. ANTIALLOANTIBODY SERUM CONTAINS SPECIFIC FACTORS REACTING WITH RELEVANT IMMUNOCOMPETENT T LYMPHOCYTES Binz, Hans Lindenmann, Jean Wigzell, Hans J Exp Med Article The rat popliteal node graft-vs.-host assay was shown to depend on the presence of parental T cells in the inoculum. Antialloantisera raised in F(1) hybrid rats against alloantibodies of one parent directed at transplantation antigens of the other parent displayed some or all of the following specific effects on parental T cells: They inhibited local GvH by purified T-cell suspensions; they blocked the capacity of GvH-reactive cells to adsorb onto fibroblast monolayers of the relevant genotype; together with complement, they killed GvH-reactive cells. The Rockefeller University Press 1974-09-01 /pmc/articles/PMC2139621/ /pubmed/4153293 Text en Copyright © 1974 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Binz, Hans
Lindenmann, Jean
Wigzell, Hans
CELL-BOUND RECEPTORS FOR ALLOANTIGENS ON NORMAL LYMPHOCYTES : II. ANTIALLOANTIBODY SERUM CONTAINS SPECIFIC FACTORS REACTING WITH RELEVANT IMMUNOCOMPETENT T LYMPHOCYTES
title CELL-BOUND RECEPTORS FOR ALLOANTIGENS ON NORMAL LYMPHOCYTES : II. ANTIALLOANTIBODY SERUM CONTAINS SPECIFIC FACTORS REACTING WITH RELEVANT IMMUNOCOMPETENT T LYMPHOCYTES
title_full CELL-BOUND RECEPTORS FOR ALLOANTIGENS ON NORMAL LYMPHOCYTES : II. ANTIALLOANTIBODY SERUM CONTAINS SPECIFIC FACTORS REACTING WITH RELEVANT IMMUNOCOMPETENT T LYMPHOCYTES
title_fullStr CELL-BOUND RECEPTORS FOR ALLOANTIGENS ON NORMAL LYMPHOCYTES : II. ANTIALLOANTIBODY SERUM CONTAINS SPECIFIC FACTORS REACTING WITH RELEVANT IMMUNOCOMPETENT T LYMPHOCYTES
title_full_unstemmed CELL-BOUND RECEPTORS FOR ALLOANTIGENS ON NORMAL LYMPHOCYTES : II. ANTIALLOANTIBODY SERUM CONTAINS SPECIFIC FACTORS REACTING WITH RELEVANT IMMUNOCOMPETENT T LYMPHOCYTES
title_short CELL-BOUND RECEPTORS FOR ALLOANTIGENS ON NORMAL LYMPHOCYTES : II. ANTIALLOANTIBODY SERUM CONTAINS SPECIFIC FACTORS REACTING WITH RELEVANT IMMUNOCOMPETENT T LYMPHOCYTES
title_sort cell-bound receptors for alloantigens on normal lymphocytes : ii. antialloantibody serum contains specific factors reacting with relevant immunocompetent t lymphocytes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139621/
https://www.ncbi.nlm.nih.gov/pubmed/4153293
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AT wigzellhans cellboundreceptorsforalloantigensonnormallymphocytesiiantialloantibodyserumcontainsspecificfactorsreactingwithrelevantimmunocompetenttlymphocytes

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