SEROLOGICAL DISTINCTION OF MUTANTS B6.C-H(z1) AND B6.M505 FROM STRAIN C57BL/6

A quantitative serological difference was found between strains Hz1 and M505 carrying mutant H-2 haplotypes ba and bd, respectively, and the original strain B6(H-2(b)). The finding suggests that the mutations occurred in the H-2K(b) gene, and together with data on MLR and CML challenges the current...

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Detalles Bibliográficos
Autores principales: Klein, Jan, Hauptfeld, Miroslav, Hauptfeld, Věra
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1974
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139645/
https://www.ncbi.nlm.nih.gov/pubmed/4139224
Descripción
Sumario:A quantitative serological difference was found between strains Hz1 and M505 carrying mutant H-2 haplotypes ba and bd, respectively, and the original strain B6(H-2(b)). The finding suggests that the mutations occurred in the H-2K(b) gene, and together with data on MLR and CML challenges the current concept of H-2 regions' involvement in immune reactions.

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