SEROLOGICAL DISTINCTION OF MUTANTS B6.C-H(z1) AND B6.M505 FROM STRAIN C57BL/6

A quantitative serological difference was found between strains Hz1 and M505 carrying mutant H-2 haplotypes ba and bd, respectively, and the original strain B6(H-2(b)). The finding suggests that the mutations occurred in the H-2K(b) gene, and together with data on MLR and CML challenges the current...

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Detalles Bibliográficos
Autores principales: Klein, Jan, Hauptfeld, Miroslav, Hauptfeld, Věra
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1974
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139645/
https://www.ncbi.nlm.nih.gov/pubmed/4139224
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author Klein, Jan
Hauptfeld, Miroslav
Hauptfeld, Věra
author_facet Klein, Jan
Hauptfeld, Miroslav
Hauptfeld, Věra
author_sort Klein, Jan
collection PubMed
description A quantitative serological difference was found between strains Hz1 and M505 carrying mutant H-2 haplotypes ba and bd, respectively, and the original strain B6(H-2(b)). The finding suggests that the mutations occurred in the H-2K(b) gene, and together with data on MLR and CML challenges the current concept of H-2 regions' involvement in immune reactions.
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spelling pubmed-21396452008-04-17 SEROLOGICAL DISTINCTION OF MUTANTS B6.C-H(z1) AND B6.M505 FROM STRAIN C57BL/6 Klein, Jan Hauptfeld, Miroslav Hauptfeld, Věra J Exp Med Brief Definitive Reports A quantitative serological difference was found between strains Hz1 and M505 carrying mutant H-2 haplotypes ba and bd, respectively, and the original strain B6(H-2(b)). The finding suggests that the mutations occurred in the H-2K(b) gene, and together with data on MLR and CML challenges the current concept of H-2 regions' involvement in immune reactions. The Rockefeller University Press 1974-10-01 /pmc/articles/PMC2139645/ /pubmed/4139224 Text en Copyright © 1974 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Brief Definitive Reports
Klein, Jan
Hauptfeld, Miroslav
Hauptfeld, Věra
SEROLOGICAL DISTINCTION OF MUTANTS B6.C-H(z1) AND B6.M505 FROM STRAIN C57BL/6
title SEROLOGICAL DISTINCTION OF MUTANTS B6.C-H(z1) AND B6.M505 FROM STRAIN C57BL/6
title_full SEROLOGICAL DISTINCTION OF MUTANTS B6.C-H(z1) AND B6.M505 FROM STRAIN C57BL/6
title_fullStr SEROLOGICAL DISTINCTION OF MUTANTS B6.C-H(z1) AND B6.M505 FROM STRAIN C57BL/6
title_full_unstemmed SEROLOGICAL DISTINCTION OF MUTANTS B6.C-H(z1) AND B6.M505 FROM STRAIN C57BL/6
title_short SEROLOGICAL DISTINCTION OF MUTANTS B6.C-H(z1) AND B6.M505 FROM STRAIN C57BL/6
title_sort serological distinction of mutants b6.c-h(z1) and b6.m505 from strain c57bl/6
topic Brief Definitive Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139645/
https://www.ncbi.nlm.nih.gov/pubmed/4139224
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