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Microtubule Stabilization in Pressure Overload Cardiac Hypertrophy
Increased microtubule density, for which microtubule stabilization is one potential mechanism, causes contractile dysfunction in cardiac hypertrophy. After microtubule assembly, α-tubulin undergoes two, likely sequential, time-dependent posttranslational changes: reversible carboxy-terminal detyrosi...
Autores principales: | Sato, Hiroshi, Nagai, Toshio, Kuppuswamy, Dhandapani, Narishige, Takahiro, Koide, Masaaki, Menick, Donald R., IV, George Cooper |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139973/ https://www.ncbi.nlm.nih.gov/pubmed/9362514 |
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