Hypo, hype and ‘hyp’ human proteins

Genes with unknown function are called orphan genes while their transcripts and peptides are called hypothetical proteins. There are many genes and their associated proteins that remain uncharacterized in the human genome. A database of human hypothetical proteins with ascribed functions could be he...

Descripción completa

Detalles Bibliográficos
Autor principal: Suravajhala, Prashanth
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2007
Materias:
Views & Challenges
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139994/
https://www.ncbi.nlm.nih.gov/pubmed/18084649
Descripción
Sumario:Genes with unknown function are called orphan genes while their transcripts and peptides are called hypothetical proteins. There are many genes and their associated proteins that remain uncharacterized in the human genome. A database of human hypothetical proteins with ascribed functions could be helpful for biologists to search for potential proteins of interest. In recent years, the rapid completion of genome sequences has created essential information to link genes to gene products. In order to better explain functions for un-annotated proteins we designed BioinformaTRICKS (an open source project) and used it to develop a database called HYPO. AVAILABILITY: The database is available for free at http://pc-dugong.ruc.dk:8080.

Ejemplares similares