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PDZRhoGEF and myosin II localize RhoA activity to the back of polarizing neutrophil-like cells
Chemoattractants such as formyl-Met-Leu-Phe (fMLP) induce neutrophils to polarize by triggering divergent pathways that promote formation of a protrusive front and contracting back and sides. RhoA, a Rho GTPase, stimulates assembly of actomyosin contractile complexes at the sides and back. We show h...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140022/ https://www.ncbi.nlm.nih.gov/pubmed/18086913 http://dx.doi.org/10.1083/jcb.200706167 |