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EGF-induced PIP(2) hydrolysis releases and activates cofilin locally in carcinoma cells
Lamellipodial protrusion and directional migration of carcinoma cells towards chemoattractants, such as epidermal growth factor (EGF), depend upon the spatial and temporal regulation of actin cytoskeleton by actin-binding proteins (ABPs). It is generally hypothesized that the activity of many ABPs a...
Autores principales: | van Rheenen, Jacco, Song, Xiaoyan, van Roosmalen, Wies, Cammer, Michael, Chen, Xiaoming, DesMarais, Vera, Yip, Shu-Chin, Backer, Jonathan M., Eddy, Robert J., Condeelis, John S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140025/ https://www.ncbi.nlm.nih.gov/pubmed/18086920 http://dx.doi.org/10.1083/jcb.200706206 |
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