Cargando…
NATURE OF THE RETARDING INFLUENCE OF THE THYMUS UPON AMPHIBIAN METAMORPHOSIS
1. Though thymus-fed salamander larvæ often metamorphose normally, thymus feeding sometimes retards and in rare cases inhibits metamorphosis completely. 2. The addition of normal food to a thymus diet abolishes the inhibitory effect of the thymus. 3. Addition of a small quantity of iodothyrin leads...
Autor principal: | |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1919
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140308/ https://www.ncbi.nlm.nih.gov/pubmed/19871747 |
_version_ | 1782143952060678144 |
---|---|
author | Uhlenhuth, Eduard |
author_facet | Uhlenhuth, Eduard |
author_sort | Uhlenhuth, Eduard |
collection | PubMed |
description | 1. Though thymus-fed salamander larvæ often metamorphose normally, thymus feeding sometimes retards and in rare cases inhibits metamorphosis completely. 2. The addition of normal food to a thymus diet abolishes the inhibitory effect of the thymus. 3. Addition of a small quantity of iodothyrin leads rapidly to precocious metamorphosis of thymus-fed larvæ. 4. The inhibitory effect of the thymus is not due to a specific inhibiting substance in the thymus, but to the absence from the thymus of a substance required to develop the thyroid to the secretory state. |
format | Text |
id | pubmed-2140308 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1919 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21403082008-04-23 NATURE OF THE RETARDING INFLUENCE OF THE THYMUS UPON AMPHIBIAN METAMORPHOSIS Uhlenhuth, Eduard J Gen Physiol Article 1. Though thymus-fed salamander larvæ often metamorphose normally, thymus feeding sometimes retards and in rare cases inhibits metamorphosis completely. 2. The addition of normal food to a thymus diet abolishes the inhibitory effect of the thymus. 3. Addition of a small quantity of iodothyrin leads rapidly to precocious metamorphosis of thymus-fed larvæ. 4. The inhibitory effect of the thymus is not due to a specific inhibiting substance in the thymus, but to the absence from the thymus of a substance required to develop the thyroid to the secretory state. The Rockefeller University Press 1919-01-20 /pmc/articles/PMC2140308/ /pubmed/19871747 Text en Copyright © Copyright, 1919, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Uhlenhuth, Eduard NATURE OF THE RETARDING INFLUENCE OF THE THYMUS UPON AMPHIBIAN METAMORPHOSIS |
title | NATURE OF THE RETARDING INFLUENCE OF THE THYMUS UPON AMPHIBIAN METAMORPHOSIS |
title_full | NATURE OF THE RETARDING INFLUENCE OF THE THYMUS UPON AMPHIBIAN METAMORPHOSIS |
title_fullStr | NATURE OF THE RETARDING INFLUENCE OF THE THYMUS UPON AMPHIBIAN METAMORPHOSIS |
title_full_unstemmed | NATURE OF THE RETARDING INFLUENCE OF THE THYMUS UPON AMPHIBIAN METAMORPHOSIS |
title_short | NATURE OF THE RETARDING INFLUENCE OF THE THYMUS UPON AMPHIBIAN METAMORPHOSIS |
title_sort | nature of the retarding influence of the thymus upon amphibian metamorphosis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140308/ https://www.ncbi.nlm.nih.gov/pubmed/19871747 |
work_keys_str_mv | AT uhlenhutheduard natureoftheretardinginfluenceofthethymusuponamphibianmetamorphosis |