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A THEORY OF INJURY AND RECOVERY : II. EXPERIMENTS WITH MIXTURES.
1. The equations which serve to predict the injury of tissue in 0.52 M NaCl and in 0.278 M CaCl(2) and its subsequent recovery (when it is replaced in sea water) also enable us to predict the behavior of tissue in mixtures of these solutions, as well as its recovery in sea water after exposure to mi...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1921
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140469/ https://www.ncbi.nlm.nih.gov/pubmed/19871875 |
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author | Osterhout, W. J. V. |
author_facet | Osterhout, W. J. V. |
author_sort | Osterhout, W. J. V. |
collection | PubMed |
description | 1. The equations which serve to predict the injury of tissue in 0.52 M NaCl and in 0.278 M CaCl(2) and its subsequent recovery (when it is replaced in sea water) also enable us to predict the behavior of tissue in mixtures of these solutions, as well as its recovery in sea water after exposure to mixtures. 2. The reactions which are assumed in order to account for the behavior of the tissue proceed as if they were inhibited by a salt compound formed by the union of NaCl and CaCl(2) with some constituent of the protoplasm (certain of these reactions are accelerated by CaCl(2)). 3. In this and preceding papers a quantitative theory is developed in order to explain: (a) the toxicity of NaCl and CaCl(2); (b) the antagonism between these substances; (c) the fact that recovery (in sea water) may be partial or complete, depending on the length of exposure to the toxic solution. |
format | Text |
id | pubmed-2140469 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1921 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21404692008-04-23 A THEORY OF INJURY AND RECOVERY : II. EXPERIMENTS WITH MIXTURES. Osterhout, W. J. V. J Gen Physiol Article 1. The equations which serve to predict the injury of tissue in 0.52 M NaCl and in 0.278 M CaCl(2) and its subsequent recovery (when it is replaced in sea water) also enable us to predict the behavior of tissue in mixtures of these solutions, as well as its recovery in sea water after exposure to mixtures. 2. The reactions which are assumed in order to account for the behavior of the tissue proceed as if they were inhibited by a salt compound formed by the union of NaCl and CaCl(2) with some constituent of the protoplasm (certain of these reactions are accelerated by CaCl(2)). 3. In this and preceding papers a quantitative theory is developed in order to explain: (a) the toxicity of NaCl and CaCl(2); (b) the antagonism between these substances; (c) the fact that recovery (in sea water) may be partial or complete, depending on the length of exposure to the toxic solution. The Rockefeller University Press 1921-03-20 /pmc/articles/PMC2140469/ /pubmed/19871875 Text en Copyright © Copyright, 1921, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Osterhout, W. J. V. A THEORY OF INJURY AND RECOVERY : II. EXPERIMENTS WITH MIXTURES. |
title | A THEORY OF INJURY AND RECOVERY : II. EXPERIMENTS WITH MIXTURES. |
title_full | A THEORY OF INJURY AND RECOVERY : II. EXPERIMENTS WITH MIXTURES. |
title_fullStr | A THEORY OF INJURY AND RECOVERY : II. EXPERIMENTS WITH MIXTURES. |
title_full_unstemmed | A THEORY OF INJURY AND RECOVERY : II. EXPERIMENTS WITH MIXTURES. |
title_short | A THEORY OF INJURY AND RECOVERY : II. EXPERIMENTS WITH MIXTURES. |
title_sort | theory of injury and recovery : ii. experiments with mixtures. |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140469/ https://www.ncbi.nlm.nih.gov/pubmed/19871875 |
work_keys_str_mv | AT osterhoutwjv atheoryofinjuryandrecoveryiiexperimentswithmixtures AT osterhoutwjv theoryofinjuryandrecoveryiiexperimentswithmixtures |