A NOTE ON THE ACTION OF CURARE, ATROPINE, AND NICOTINE ON THE INVERTEBRATE HEART

1. The alkaloids (curare, atropine, and nicotine) in molluscs and arthropods stimulate and paralyze the central nervous system and peripheral (visceral) ganglia, but do not paralyze the motor nerve endings to skeletal or visceral muscle. 2. They stimulate and paralyze the denervated heart. 3. They p...

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Detalles Bibliográficos
Autor principal: Carlson, A. J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1922
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140520/
https://www.ncbi.nlm.nih.gov/pubmed/19871954
Descripción
Sumario:1. The alkaloids (curare, atropine, and nicotine) in molluscs and arthropods stimulate and paralyze the central nervous system and peripheral (visceral) ganglia, but do not paralyze the motor nerve endings to skeletal or visceral muscle. 2. They stimulate and paralyze the denervated heart. 3. They paralyze or block the cardioinhibitory nerves, but not the cardioaccelerator nerves. 4. In the Limulus heart these drugs act primarily on the heart ganglion, not on the heart muscle or the intrinsic motor nerve fibers.

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