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A NOTE ON THE ACTION OF CURARE, ATROPINE, AND NICOTINE ON THE INVERTEBRATE HEART
1. The alkaloids (curare, atropine, and nicotine) in molluscs and arthropods stimulate and paralyze the central nervous system and peripheral (visceral) ganglia, but do not paralyze the motor nerve endings to skeletal or visceral muscle. 2. They stimulate and paralyze the denervated heart. 3. They p...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1922
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140520/ https://www.ncbi.nlm.nih.gov/pubmed/19871954 |
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author | Carlson, A. J. |
author_facet | Carlson, A. J. |
author_sort | Carlson, A. J. |
collection | PubMed |
description | 1. The alkaloids (curare, atropine, and nicotine) in molluscs and arthropods stimulate and paralyze the central nervous system and peripheral (visceral) ganglia, but do not paralyze the motor nerve endings to skeletal or visceral muscle. 2. They stimulate and paralyze the denervated heart. 3. They paralyze or block the cardioinhibitory nerves, but not the cardioaccelerator nerves. 4. In the Limulus heart these drugs act primarily on the heart ganglion, not on the heart muscle or the intrinsic motor nerve fibers. |
format | Text |
id | pubmed-2140520 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1922 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21405202008-04-23 A NOTE ON THE ACTION OF CURARE, ATROPINE, AND NICOTINE ON THE INVERTEBRATE HEART Carlson, A. J. J Gen Physiol Article 1. The alkaloids (curare, atropine, and nicotine) in molluscs and arthropods stimulate and paralyze the central nervous system and peripheral (visceral) ganglia, but do not paralyze the motor nerve endings to skeletal or visceral muscle. 2. They stimulate and paralyze the denervated heart. 3. They paralyze or block the cardioinhibitory nerves, but not the cardioaccelerator nerves. 4. In the Limulus heart these drugs act primarily on the heart ganglion, not on the heart muscle or the intrinsic motor nerve fibers. The Rockefeller University Press 1922-05-20 /pmc/articles/PMC2140520/ /pubmed/19871954 Text en Copyright © Copyright, 1922, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Carlson, A. J. A NOTE ON THE ACTION OF CURARE, ATROPINE, AND NICOTINE ON THE INVERTEBRATE HEART |
title | A NOTE ON THE ACTION OF CURARE, ATROPINE, AND NICOTINE ON THE INVERTEBRATE HEART |
title_full | A NOTE ON THE ACTION OF CURARE, ATROPINE, AND NICOTINE ON THE INVERTEBRATE HEART |
title_fullStr | A NOTE ON THE ACTION OF CURARE, ATROPINE, AND NICOTINE ON THE INVERTEBRATE HEART |
title_full_unstemmed | A NOTE ON THE ACTION OF CURARE, ATROPINE, AND NICOTINE ON THE INVERTEBRATE HEART |
title_short | A NOTE ON THE ACTION OF CURARE, ATROPINE, AND NICOTINE ON THE INVERTEBRATE HEART |
title_sort | note on the action of curare, atropine, and nicotine on the invertebrate heart |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140520/ https://www.ncbi.nlm.nih.gov/pubmed/19871954 |
work_keys_str_mv | AT carlsonaj anoteontheactionofcurareatropineandnicotineontheinvertebrateheart AT carlsonaj noteontheactionofcurareatropineandnicotineontheinvertebrateheart |