SPEED OF TOXIC ACTION OF ARSENIC IN THE SILKWORM

A micro burette, micro pipette, and methods for their use in quantitative toxicological investigations on mandibulate insects are described. It is suggested that the form of curves relating speed of toxic action to dosage may be explained by postulating suitable changes in rate of distribution, excr...

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Detalles Bibliográficos
Autor principal: Campbell, F. L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1926
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140834/
https://www.ncbi.nlm.nih.gov/pubmed/19872265
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author Campbell, F. L.
author_facet Campbell, F. L.
author_sort Campbell, F. L.
collection PubMed
description A micro burette, micro pipette, and methods for their use in quantitative toxicological investigations on mandibulate insects are described. It is suggested that the form of curves relating speed of toxic action to dosage may be explained by postulating suitable changes in rate of distribution, excretion, and cell penetration of poison as dosage varies. The speed of toxic action of pentavalent arsenic in the silkworm is proportional to an integral power of the dosage at lower concentrations, and to a fractional power of the dosage at higher concentrations.
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spelling pubmed-21408342008-04-23 SPEED OF TOXIC ACTION OF ARSENIC IN THE SILKWORM Campbell, F. L. J Gen Physiol Article A micro burette, micro pipette, and methods for their use in quantitative toxicological investigations on mandibulate insects are described. It is suggested that the form of curves relating speed of toxic action to dosage may be explained by postulating suitable changes in rate of distribution, excretion, and cell penetration of poison as dosage varies. The speed of toxic action of pentavalent arsenic in the silkworm is proportional to an integral power of the dosage at lower concentrations, and to a fractional power of the dosage at higher concentrations. The Rockefeller University Press 1926-03-20 /pmc/articles/PMC2140834/ /pubmed/19872265 Text en Copyright © Copyright, 1926, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Campbell, F. L.
SPEED OF TOXIC ACTION OF ARSENIC IN THE SILKWORM
title SPEED OF TOXIC ACTION OF ARSENIC IN THE SILKWORM
title_full SPEED OF TOXIC ACTION OF ARSENIC IN THE SILKWORM
title_fullStr SPEED OF TOXIC ACTION OF ARSENIC IN THE SILKWORM
title_full_unstemmed SPEED OF TOXIC ACTION OF ARSENIC IN THE SILKWORM
title_short SPEED OF TOXIC ACTION OF ARSENIC IN THE SILKWORM
title_sort speed of toxic action of arsenic in the silkworm
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140834/
https://www.ncbi.nlm.nih.gov/pubmed/19872265
work_keys_str_mv AT campbellfl speedoftoxicactionofarsenicinthesilkworm

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