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THE TOXIC ACTION OF COPPER ON NITELLA
1. Using the loss of turgidity of the cells as a criterion it is found that the toxicity curve of copper chloride with Nitella is sigmoid. An empirical equation can be constructed which will approximately fit the curve. 2. When the concentration of the copper chloride is varied the toxic effect vari...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1926
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140897/ https://www.ncbi.nlm.nih.gov/pubmed/19872288 |
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author | Cook, S. F. |
author_facet | Cook, S. F. |
author_sort | Cook, S. F. |
collection | PubMed |
description | 1. Using the loss of turgidity of the cells as a criterion it is found that the toxicity curve of copper chloride with Nitella is sigmoid. An empirical equation can be constructed which will approximately fit the curve. 2. When the concentration of the copper chloride is varied the toxic effect varies as a constant, fractional, power of the concentration. This relation holds when the concentration is plotted against either (1) the time necessary to reach a given point on the ordinate of the survivor curve, (2) the maximum speed of toxic action as shown by the tangent to the survivor curve or (3) the first derivative of the equation which fits the survivor curve. 3. When the temperature is varied and the logarithm of the reciprocal of the time necessary to reach a given point on the survivor curves is plotted against the reciprocal of the absolute temperature the resulting figure consists of several intersecting curves. A hypothetical system is described which will give straight lines under normal conditions and curves when acted upon by a toxic agent. |
format | Text |
id | pubmed-2140897 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1926 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21408972008-04-23 THE TOXIC ACTION OF COPPER ON NITELLA Cook, S. F. J Gen Physiol Article 1. Using the loss of turgidity of the cells as a criterion it is found that the toxicity curve of copper chloride with Nitella is sigmoid. An empirical equation can be constructed which will approximately fit the curve. 2. When the concentration of the copper chloride is varied the toxic effect varies as a constant, fractional, power of the concentration. This relation holds when the concentration is plotted against either (1) the time necessary to reach a given point on the ordinate of the survivor curve, (2) the maximum speed of toxic action as shown by the tangent to the survivor curve or (3) the first derivative of the equation which fits the survivor curve. 3. When the temperature is varied and the logarithm of the reciprocal of the time necessary to reach a given point on the survivor curves is plotted against the reciprocal of the absolute temperature the resulting figure consists of several intersecting curves. A hypothetical system is described which will give straight lines under normal conditions and curves when acted upon by a toxic agent. The Rockefeller University Press 1926-07-20 /pmc/articles/PMC2140897/ /pubmed/19872288 Text en Copyright © Copyright, 1926, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Cook, S. F. THE TOXIC ACTION OF COPPER ON NITELLA |
title | THE TOXIC ACTION OF COPPER ON NITELLA |
title_full | THE TOXIC ACTION OF COPPER ON NITELLA |
title_fullStr | THE TOXIC ACTION OF COPPER ON NITELLA |
title_full_unstemmed | THE TOXIC ACTION OF COPPER ON NITELLA |
title_short | THE TOXIC ACTION OF COPPER ON NITELLA |
title_sort | toxic action of copper on nitella |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140897/ https://www.ncbi.nlm.nih.gov/pubmed/19872288 |
work_keys_str_mv | AT cooksf thetoxicactionofcopperonnitella AT cooksf toxicactionofcopperonnitella |