GALVANOTROPISM AND "REVERSAL OF INHIBITION" BY STRYCHNINE

The cathodically galvanotropic orientation of nemerteans, Lineus, and the anodic orientation of the gephyrean Echiurus, are reversed by the action of strychnine under conditions such that the typical "reversal of inhibition" induced by this substance is apparent. Nicotine does not give thi...

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Detalles Bibliográficos
Autor principal: Crozier, W. J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1927
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140911/
https://www.ncbi.nlm.nih.gov/pubmed/19872331
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author Crozier, W. J.
author_facet Crozier, W. J.
author_sort Crozier, W. J.
collection PubMed
description The cathodically galvanotropic orientation of nemerteans, Lineus, and the anodic orientation of the gephyrean Echiurus, are reversed by the action of strychnine under conditions such that the typical "reversal of inhibition" induced by this substance is apparent. Nicotine does not give this result. Since it is necessary to assume that the strychnine effect is due to action upon the central ganglia, and since the galvanotropic effect depends upon action of the current on nerve cell bodies of the central ganglia, it must be assumed that the locus of reversal by strychnine is not perikaryal, but presumably synaptic.
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spelling pubmed-21409112008-04-23 GALVANOTROPISM AND "REVERSAL OF INHIBITION" BY STRYCHNINE Crozier, W. J. J Gen Physiol Article The cathodically galvanotropic orientation of nemerteans, Lineus, and the anodic orientation of the gephyrean Echiurus, are reversed by the action of strychnine under conditions such that the typical "reversal of inhibition" induced by this substance is apparent. Nicotine does not give this result. Since it is necessary to assume that the strychnine effect is due to action upon the central ganglia, and since the galvanotropic effect depends upon action of the current on nerve cell bodies of the central ganglia, it must be assumed that the locus of reversal by strychnine is not perikaryal, but presumably synaptic. The Rockefeller University Press 1927-01-20 /pmc/articles/PMC2140911/ /pubmed/19872331 Text en Copyright © Copyright, 1927, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Crozier, W. J.
GALVANOTROPISM AND "REVERSAL OF INHIBITION" BY STRYCHNINE
title GALVANOTROPISM AND "REVERSAL OF INHIBITION" BY STRYCHNINE
title_full GALVANOTROPISM AND "REVERSAL OF INHIBITION" BY STRYCHNINE
title_fullStr GALVANOTROPISM AND "REVERSAL OF INHIBITION" BY STRYCHNINE
title_full_unstemmed GALVANOTROPISM AND "REVERSAL OF INHIBITION" BY STRYCHNINE
title_short GALVANOTROPISM AND "REVERSAL OF INHIBITION" BY STRYCHNINE
title_sort galvanotropism and "reversal of inhibition" by strychnine
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140911/
https://www.ncbi.nlm.nih.gov/pubmed/19872331
work_keys_str_mv AT crozierwj galvanotropismandreversalofinhibitionbystrychnine

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