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ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS
1. The theory of the serial dilution method of titration of bacterio-phage has been worked out on the basis of the simple particulate hypothesis. 2. It has been shown that, if the dilution constant is .1, only about 60 per cent of parallel runs on the same solution should give the same end-point, th...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1927
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140959/ https://www.ncbi.nlm.nih.gov/pubmed/19872381 |
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author | Clark, Harry |
author_facet | Clark, Harry |
author_sort | Clark, Harry |
collection | PubMed |
description | 1. The theory of the serial dilution method of titration of bacterio-phage has been worked out on the basis of the simple particulate hypothesis. 2. It has been shown that, if the dilution constant is .1, only about 60 per cent of parallel runs on the same solution should give the same end-point, the average being taken over a great number of titrations of each of a great variety of solutions. 3. The discrepancy between this figure, 60 per cent, and Dr. Bronfenbrenner's estimate, 85 per cent, is considerable. 4. Inasmuch as the particulate hypothesis is well founded, no explanation of the discrepancy is suggested. |
format | Text |
id | pubmed-2140959 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1927 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21409592008-04-23 ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS Clark, Harry J Gen Physiol Article 1. The theory of the serial dilution method of titration of bacterio-phage has been worked out on the basis of the simple particulate hypothesis. 2. It has been shown that, if the dilution constant is .1, only about 60 per cent of parallel runs on the same solution should give the same end-point, the average being taken over a great number of titrations of each of a great variety of solutions. 3. The discrepancy between this figure, 60 per cent, and Dr. Bronfenbrenner's estimate, 85 per cent, is considerable. 4. Inasmuch as the particulate hypothesis is well founded, no explanation of the discrepancy is suggested. The Rockefeller University Press 1927-09-20 /pmc/articles/PMC2140959/ /pubmed/19872381 Text en Copyright © Copyright, 1927, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Clark, Harry ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS |
title | ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS |
title_full | ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS |
title_fullStr | ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS |
title_full_unstemmed | ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS |
title_short | ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS |
title_sort | on the titration of bacteriophage and the particulate hypothesis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140959/ https://www.ncbi.nlm.nih.gov/pubmed/19872381 |
work_keys_str_mv | AT clarkharry onthetitrationofbacteriophageandtheparticulatehypothesis |