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ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS

1. The theory of the serial dilution method of titration of bacterio-phage has been worked out on the basis of the simple particulate hypothesis. 2. It has been shown that, if the dilution constant is .1, only about 60 per cent of parallel runs on the same solution should give the same end-point, th...

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Detalles Bibliográficos
Autor principal: Clark, Harry
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1927
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140959/
https://www.ncbi.nlm.nih.gov/pubmed/19872381
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author Clark, Harry
author_facet Clark, Harry
author_sort Clark, Harry
collection PubMed
description 1. The theory of the serial dilution method of titration of bacterio-phage has been worked out on the basis of the simple particulate hypothesis. 2. It has been shown that, if the dilution constant is .1, only about 60 per cent of parallel runs on the same solution should give the same end-point, the average being taken over a great number of titrations of each of a great variety of solutions. 3. The discrepancy between this figure, 60 per cent, and Dr. Bronfenbrenner's estimate, 85 per cent, is considerable. 4. Inasmuch as the particulate hypothesis is well founded, no explanation of the discrepancy is suggested.
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spelling pubmed-21409592008-04-23 ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS Clark, Harry J Gen Physiol Article 1. The theory of the serial dilution method of titration of bacterio-phage has been worked out on the basis of the simple particulate hypothesis. 2. It has been shown that, if the dilution constant is .1, only about 60 per cent of parallel runs on the same solution should give the same end-point, the average being taken over a great number of titrations of each of a great variety of solutions. 3. The discrepancy between this figure, 60 per cent, and Dr. Bronfenbrenner's estimate, 85 per cent, is considerable. 4. Inasmuch as the particulate hypothesis is well founded, no explanation of the discrepancy is suggested. The Rockefeller University Press 1927-09-20 /pmc/articles/PMC2140959/ /pubmed/19872381 Text en Copyright © Copyright, 1927, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Clark, Harry
ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS
title ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS
title_full ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS
title_fullStr ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS
title_full_unstemmed ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS
title_short ON THE TITRATION OF BACTERIOPHAGE AND THE PARTICULATE HYPOTHESIS
title_sort on the titration of bacteriophage and the particulate hypothesis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140959/
https://www.ncbi.nlm.nih.gov/pubmed/19872381
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