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THE ANTAGONISM BETWEEN ACETIC ACID AND THE CHLORIDES OF SODIUM, POTASSIUM, AND CALCIUM AS MANIFESTED IN DEVELOPING FUNDULUS EMBRYOS
1. Developing Fundulus embryos react in much the same way to mixtures of acetic acid in salt solutions whether their membranes are removed or not. It is therefore not necessary to assume any specific rôle for the membrane. 2. The primary toxic effect of acetic acid is to kill the surface of the embr...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1928
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140993/ https://www.ncbi.nlm.nih.gov/pubmed/19872417 |
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author | Armstrong, Philip B. |
author_facet | Armstrong, Philip B. |
author_sort | Armstrong, Philip B. |
collection | PubMed |
description | 1. Developing Fundulus embryos react in much the same way to mixtures of acetic acid in salt solutions whether their membranes are removed or not. It is therefore not necessary to assume any specific rôle for the membrane. 2. The primary toxic effect of acetic acid is to kill the surface of the embryo; heart stoppage is due to penetration of the acid after the surface has been injured. 3. The salt (NaCl, KCl, CaCl(2)) antagonizes the acetic acid by slowing or preventing the killing of the surface of the embryo. 4. If embryos are immersed in certain KCl-acetic acid mixtures, the surface killing effect of the acid is antagonized but at the same time the KCl penetrates and stops the heart in the manner which is characteristic of a KCl solution alone. |
format | Text |
id | pubmed-2140993 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1928 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21409932008-04-23 THE ANTAGONISM BETWEEN ACETIC ACID AND THE CHLORIDES OF SODIUM, POTASSIUM, AND CALCIUM AS MANIFESTED IN DEVELOPING FUNDULUS EMBRYOS Armstrong, Philip B. J Gen Physiol Article 1. Developing Fundulus embryos react in much the same way to mixtures of acetic acid in salt solutions whether their membranes are removed or not. It is therefore not necessary to assume any specific rôle for the membrane. 2. The primary toxic effect of acetic acid is to kill the surface of the embryo; heart stoppage is due to penetration of the acid after the surface has been injured. 3. The salt (NaCl, KCl, CaCl(2)) antagonizes the acetic acid by slowing or preventing the killing of the surface of the embryo. 4. If embryos are immersed in certain KCl-acetic acid mixtures, the surface killing effect of the acid is antagonized but at the same time the KCl penetrates and stops the heart in the manner which is characteristic of a KCl solution alone. The Rockefeller University Press 1928-05-20 /pmc/articles/PMC2140993/ /pubmed/19872417 Text en Copyright © Copyright, 1928, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Armstrong, Philip B. THE ANTAGONISM BETWEEN ACETIC ACID AND THE CHLORIDES OF SODIUM, POTASSIUM, AND CALCIUM AS MANIFESTED IN DEVELOPING FUNDULUS EMBRYOS |
title | THE ANTAGONISM BETWEEN ACETIC ACID AND THE CHLORIDES OF SODIUM, POTASSIUM, AND CALCIUM AS MANIFESTED IN DEVELOPING FUNDULUS EMBRYOS |
title_full | THE ANTAGONISM BETWEEN ACETIC ACID AND THE CHLORIDES OF SODIUM, POTASSIUM, AND CALCIUM AS MANIFESTED IN DEVELOPING FUNDULUS EMBRYOS |
title_fullStr | THE ANTAGONISM BETWEEN ACETIC ACID AND THE CHLORIDES OF SODIUM, POTASSIUM, AND CALCIUM AS MANIFESTED IN DEVELOPING FUNDULUS EMBRYOS |
title_full_unstemmed | THE ANTAGONISM BETWEEN ACETIC ACID AND THE CHLORIDES OF SODIUM, POTASSIUM, AND CALCIUM AS MANIFESTED IN DEVELOPING FUNDULUS EMBRYOS |
title_short | THE ANTAGONISM BETWEEN ACETIC ACID AND THE CHLORIDES OF SODIUM, POTASSIUM, AND CALCIUM AS MANIFESTED IN DEVELOPING FUNDULUS EMBRYOS |
title_sort | antagonism between acetic acid and the chlorides of sodium, potassium, and calcium as manifested in developing fundulus embryos |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2140993/ https://www.ncbi.nlm.nih.gov/pubmed/19872417 |
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