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PROTEIN COAGULATION AND ITS REVERSAL : THE PREPARATION OF INSOLUBLE GLOBIN, SOLUBLE GLOBIN AND HEME
1. By a procedure involving the use of acid acetone hemoglobin may be rapidly separated into a precipitate of denatured globin and an acetone solution of heme. 2. By neutralization procedures the denatured globin may be largely converted into a soluble, apparently native form which can combine with...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1930
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141062/ https://www.ncbi.nlm.nih.gov/pubmed/19872539 |
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author | Anson, M. L. Mirsky, A. E. |
author_facet | Anson, M. L. Mirsky, A. E. |
author_sort | Anson, M. L. |
collection | PubMed |
description | 1. By a procedure involving the use of acid acetone hemoglobin may be rapidly separated into a precipitate of denatured globin and an acetone solution of heme. 2. By neutralization procedures the denatured globin may be largely converted into a soluble, apparently native form which can combine with heme to form hemoglobin. 3. The heme may be obtained in acetone-free, slightly alkaline solution without the use of strong alkali which may modify the heme. |
format | Text |
id | pubmed-2141062 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1930 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21410622008-04-23 PROTEIN COAGULATION AND ITS REVERSAL : THE PREPARATION OF INSOLUBLE GLOBIN, SOLUBLE GLOBIN AND HEME Anson, M. L. Mirsky, A. E. J Gen Physiol Article 1. By a procedure involving the use of acid acetone hemoglobin may be rapidly separated into a precipitate of denatured globin and an acetone solution of heme. 2. By neutralization procedures the denatured globin may be largely converted into a soluble, apparently native form which can combine with heme to form hemoglobin. 3. The heme may be obtained in acetone-free, slightly alkaline solution without the use of strong alkali which may modify the heme. The Rockefeller University Press 1930-03-20 /pmc/articles/PMC2141062/ /pubmed/19872539 Text en Copyright © Copyright, 1930, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Anson, M. L. Mirsky, A. E. PROTEIN COAGULATION AND ITS REVERSAL : THE PREPARATION OF INSOLUBLE GLOBIN, SOLUBLE GLOBIN AND HEME |
title | PROTEIN COAGULATION AND ITS REVERSAL : THE PREPARATION OF INSOLUBLE GLOBIN, SOLUBLE GLOBIN AND HEME |
title_full | PROTEIN COAGULATION AND ITS REVERSAL : THE PREPARATION OF INSOLUBLE GLOBIN, SOLUBLE GLOBIN AND HEME |
title_fullStr | PROTEIN COAGULATION AND ITS REVERSAL : THE PREPARATION OF INSOLUBLE GLOBIN, SOLUBLE GLOBIN AND HEME |
title_full_unstemmed | PROTEIN COAGULATION AND ITS REVERSAL : THE PREPARATION OF INSOLUBLE GLOBIN, SOLUBLE GLOBIN AND HEME |
title_short | PROTEIN COAGULATION AND ITS REVERSAL : THE PREPARATION OF INSOLUBLE GLOBIN, SOLUBLE GLOBIN AND HEME |
title_sort | protein coagulation and its reversal : the preparation of insoluble globin, soluble globin and heme |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141062/ https://www.ncbi.nlm.nih.gov/pubmed/19872539 |
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