THE OCCURRENCE OF PORPHYRINS IN CULTURES OF C. DIPHTHERIAE

A complex porphyrin which has not been hitherto described is found in liquid cultures of C. diphtheriae. The porphyrin is a combination of coproporphyrin with both iron and copper, and shows an oxidation-reduction change. This is the first report, as far as we are able to determine, of a porphyrin c...

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Detalles Bibliográficos
Autores principales: Coulter, Calvin B., Stone, Florence M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1931
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141129/
https://www.ncbi.nlm.nih.gov/pubmed/19872607
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author Coulter, Calvin B.
Stone, Florence M.
author_facet Coulter, Calvin B.
Stone, Florence M.
author_sort Coulter, Calvin B.
collection PubMed
description A complex porphyrin which has not been hitherto described is found in liquid cultures of C. diphtheriae. The porphyrin is a combination of coproporphyrin with both iron and copper, and shows an oxidation-reduction change. This is the first report, as far as we are able to determine, of a porphyrin compound which contains both iron and copper in its molecule. Its source is in all probability the cytochome of the bacilli. The content of porphyrin is proportional to the biological titer of the culture filtrate; the suggestion is offered that the toxin itself is derived from cytochrome.
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spelling pubmed-21411292008-04-23 THE OCCURRENCE OF PORPHYRINS IN CULTURES OF C. DIPHTHERIAE Coulter, Calvin B. Stone, Florence M. J Gen Physiol Article A complex porphyrin which has not been hitherto described is found in liquid cultures of C. diphtheriae. The porphyrin is a combination of coproporphyrin with both iron and copper, and shows an oxidation-reduction change. This is the first report, as far as we are able to determine, of a porphyrin compound which contains both iron and copper in its molecule. Its source is in all probability the cytochome of the bacilli. The content of porphyrin is proportional to the biological titer of the culture filtrate; the suggestion is offered that the toxin itself is derived from cytochrome. The Rockefeller University Press 1931-05-20 /pmc/articles/PMC2141129/ /pubmed/19872607 Text en Copyright © Copyright, 1931, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Coulter, Calvin B.
Stone, Florence M.
THE OCCURRENCE OF PORPHYRINS IN CULTURES OF C. DIPHTHERIAE
title THE OCCURRENCE OF PORPHYRINS IN CULTURES OF C. DIPHTHERIAE
title_full THE OCCURRENCE OF PORPHYRINS IN CULTURES OF C. DIPHTHERIAE
title_fullStr THE OCCURRENCE OF PORPHYRINS IN CULTURES OF C. DIPHTHERIAE
title_full_unstemmed THE OCCURRENCE OF PORPHYRINS IN CULTURES OF C. DIPHTHERIAE
title_short THE OCCURRENCE OF PORPHYRINS IN CULTURES OF C. DIPHTHERIAE
title_sort occurrence of porphyrins in cultures of c. diphtheriae
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141129/
https://www.ncbi.nlm.nih.gov/pubmed/19872607
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