THE COUPLED REDOX POTENTIAL OF THE LACTATE-ENZYME-PYRUVATE SYSTEM

1. The term "coupled redox potential" is defined. 2. The system lactic ion See PDF for Equation pyruvic ion + 2H(+) + 2e is shown to be reversible (when the enzyme is lactic acid dehydrogenase) and its coupled redox potential between pH 5.2 and 7.2 at 32°C. is: See PDF for Equation 3. The...

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Autores principales: Baumberger, J. Percy, Jürgensen, J. J., Bardwell, Kathleen
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1933
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141256/
https://www.ncbi.nlm.nih.gov/pubmed/19872753
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author Baumberger, J. Percy
Jürgensen, J. J.
Bardwell, Kathleen
author_facet Baumberger, J. Percy
Jürgensen, J. J.
Bardwell, Kathleen
author_sort Baumberger, J. Percy
collection PubMed
description 1. The term "coupled redox potential" is defined. 2. The system lactic ion See PDF for Equation pyruvic ion + 2H(+) + 2e is shown to be reversible (when the enzyme is lactic acid dehydrogenase) and its coupled redox potential between pH 5.2 and 7.2 at 32°C. is: See PDF for Equation 3. The free energy of the reaction: lactic ion (1m) → pyruvic ion (1m) = -ΔF = –14,572. 4. The standard free energy of formation (ΔF (298)) of pyruvic acid (l) is estimated at –108,127. This is merely an approximation as some necessary data are lacking. 5. The importance of coupled redox potentials as a factor in the regulation of the equilibrium of metabolites is indicated.
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spelling pubmed-21412562008-04-23 THE COUPLED REDOX POTENTIAL OF THE LACTATE-ENZYME-PYRUVATE SYSTEM Baumberger, J. Percy Jürgensen, J. J. Bardwell, Kathleen J Gen Physiol Article 1. The term "coupled redox potential" is defined. 2. The system lactic ion See PDF for Equation pyruvic ion + 2H(+) + 2e is shown to be reversible (when the enzyme is lactic acid dehydrogenase) and its coupled redox potential between pH 5.2 and 7.2 at 32°C. is: See PDF for Equation 3. The free energy of the reaction: lactic ion (1m) → pyruvic ion (1m) = -ΔF = –14,572. 4. The standard free energy of formation (ΔF (298)) of pyruvic acid (l) is estimated at –108,127. This is merely an approximation as some necessary data are lacking. 5. The importance of coupled redox potentials as a factor in the regulation of the equilibrium of metabolites is indicated. The Rockefeller University Press 1933-07-20 /pmc/articles/PMC2141256/ /pubmed/19872753 Text en Copyright © Copyright, 1933, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Baumberger, J. Percy
Jürgensen, J. J.
Bardwell, Kathleen
THE COUPLED REDOX POTENTIAL OF THE LACTATE-ENZYME-PYRUVATE SYSTEM
title THE COUPLED REDOX POTENTIAL OF THE LACTATE-ENZYME-PYRUVATE SYSTEM
title_full THE COUPLED REDOX POTENTIAL OF THE LACTATE-ENZYME-PYRUVATE SYSTEM
title_fullStr THE COUPLED REDOX POTENTIAL OF THE LACTATE-ENZYME-PYRUVATE SYSTEM
title_full_unstemmed THE COUPLED REDOX POTENTIAL OF THE LACTATE-ENZYME-PYRUVATE SYSTEM
title_short THE COUPLED REDOX POTENTIAL OF THE LACTATE-ENZYME-PYRUVATE SYSTEM
title_sort coupled redox potential of the lactate-enzyme-pyruvate system
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141256/
https://www.ncbi.nlm.nih.gov/pubmed/19872753
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