ON GUAIACOL SOLUTIONS : II. THE DISTRIBUTION OF SODIUM AND POTASSIUM GUAIACOLATES BETWEEN GUAIACOL AND WATER

1. Measurements are reported on the distribution of sodium and potassium guaiacolates between guaiacol and water at 25°C. 2. The variation of the partition coefficients with the concentration is explained with the aid of the Debye-Hückel interionic attraction theory and the assumption that the salts are strong electrolytes in water and weak electrolytes in guaiacol. 3. The dissociation constants of sodium and potassium guaiacolates in guaiacol previously computed from electrical conductivity determinations are shown to be in agreement with the corresponding values obtained from the distribution measurements. 4. From theoretical considerations an equation is derived with which it is possible to predict the magnitude of the limiting partition coefficients from the dielectric constants of the solvents, the size of the solute ions, and the temperature.