THE POTENTIAL AND RESPIRATION OF FROG SKIN : I. THE EFFECT OF THE HOMOLOGOUS CARBAMATES. II. THE EFFECT OF CERTAIN LYSINS

Measurements of the O(2) consumption and of the potential of frog skin, made under comparable conditions, show that the homologous carbamates (ethyl, propyl, butyl, and amyl) reduce both the O(2) consumption and the potential, but not in a similar manner. In this respect, the effect of the carbamate...

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Detalles Bibliográficos
Autores principales: Ponder, Eric, Macleod, John
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1937
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141497/
https://www.ncbi.nlm.nih.gov/pubmed/19873000
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author Ponder, Eric
Macleod, John
author_facet Ponder, Eric
Macleod, John
author_sort Ponder, Eric
collection PubMed
description Measurements of the O(2) consumption and of the potential of frog skin, made under comparable conditions, show that the homologous carbamates (ethyl, propyl, butyl, and amyl) reduce both the O(2) consumption and the potential, but not in a similar manner. In this respect, the effect of the carbamates is like the effect of reduction in O(2) tension. The simple lysins (saponin and the bile salts), on the other hand, abolish the potential without reducing the O(2) consumption at all. Irrespective of whether one considers the concentration of carbamate in the entire system or the amount of carbamate adsorbed by the frog skin, Traube's rule relating the effect of a carbamate to its position in the homologous series does not seem to apply.
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spelling pubmed-21414972008-04-23 THE POTENTIAL AND RESPIRATION OF FROG SKIN : I. THE EFFECT OF THE HOMOLOGOUS CARBAMATES. II. THE EFFECT OF CERTAIN LYSINS Ponder, Eric Macleod, John J Gen Physiol Article Measurements of the O(2) consumption and of the potential of frog skin, made under comparable conditions, show that the homologous carbamates (ethyl, propyl, butyl, and amyl) reduce both the O(2) consumption and the potential, but not in a similar manner. In this respect, the effect of the carbamates is like the effect of reduction in O(2) tension. The simple lysins (saponin and the bile salts), on the other hand, abolish the potential without reducing the O(2) consumption at all. Irrespective of whether one considers the concentration of carbamate in the entire system or the amount of carbamate adsorbed by the frog skin, Traube's rule relating the effect of a carbamate to its position in the homologous series does not seem to apply. The Rockefeller University Press 1937-01-20 /pmc/articles/PMC2141497/ /pubmed/19873000 Text en Copyright © Copyright, 1937, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Ponder, Eric
Macleod, John
THE POTENTIAL AND RESPIRATION OF FROG SKIN : I. THE EFFECT OF THE HOMOLOGOUS CARBAMATES. II. THE EFFECT OF CERTAIN LYSINS
title THE POTENTIAL AND RESPIRATION OF FROG SKIN : I. THE EFFECT OF THE HOMOLOGOUS CARBAMATES. II. THE EFFECT OF CERTAIN LYSINS
title_full THE POTENTIAL AND RESPIRATION OF FROG SKIN : I. THE EFFECT OF THE HOMOLOGOUS CARBAMATES. II. THE EFFECT OF CERTAIN LYSINS
title_fullStr THE POTENTIAL AND RESPIRATION OF FROG SKIN : I. THE EFFECT OF THE HOMOLOGOUS CARBAMATES. II. THE EFFECT OF CERTAIN LYSINS
title_full_unstemmed THE POTENTIAL AND RESPIRATION OF FROG SKIN : I. THE EFFECT OF THE HOMOLOGOUS CARBAMATES. II. THE EFFECT OF CERTAIN LYSINS
title_short THE POTENTIAL AND RESPIRATION OF FROG SKIN : I. THE EFFECT OF THE HOMOLOGOUS CARBAMATES. II. THE EFFECT OF CERTAIN LYSINS
title_sort potential and respiration of frog skin : i. the effect of the homologous carbamates. ii. the effect of certain lysins
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141497/
https://www.ncbi.nlm.nih.gov/pubmed/19873000
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