Cargando…
The Guanine Nucleotide Exchange Factor Tiam1 Affects Neuronal Morphology; Opposing Roles for the Small GTPases Rac and Rho
The invasion-inducing T-lymphoma invasion and metastasis 1 (Tiam1) protein functions as a guanine nucleotide exchange factor (GEF) for the small GTPase Rac1. Differentiation-dependent expression of Tiam1 in the developing brain suggests a role for this GEF and its effector Rac1 in the control of neu...
Autores principales: | van Leeuwen, Frank N., Kain, Hendrie E.T., van der Kammen, Rob A., Michiels, Frits, Kranenburg, Onno W., Collard, John G. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141700/ https://www.ncbi.nlm.nih.gov/pubmed/9348295 |
Ejemplares similares
-
Matrix-dependent Tiam1/Rac Signaling in Epithelial Cells Promotes Either Cell–Cell Adhesion or Cell Migration and Is Regulated by Phosphatidylinositol 3-Kinase
por: Sander, Eva E., et al.
Publicado: (1998) -
Dendrite regeneration in C. elegans is controlled by the RAC GTPase CED-10 and the RhoGEF TIAM-1
por: Brar, Harjot Kaur, et al.
Publicado: (2022) -
Opposing roles of hematopoietic-specific small GTPase Rac2 and the guanine nucleotide exchange factor Vav1 in osteoclast differentiation
por: Kang, In Soon, et al.
Publicado: (2020) -
Regulated Membrane Localization of Tiam1, Mediated by the NH(2)-terminal Pleckstrin Homology Domain, Is Required for Rac-dependent Membrane Ruffling and C-Jun NH(2)-terminal Kinase Activation
por: Michiels, Frits, et al.
Publicado: (1997) -
Rac Downregulates Rho Activity: Reciprocal Balance between Both Gtpases Determines Cellular Morphology and Migratory Behavior
por: Sander, Eva E., et al.
Publicado: (1999)