Novel octavalent cross-linker displays efficient trapping of protein–protein interactions

A novel octavalent, resorcin[4]arene derived, cross-linker designed to overcome some of the limitations of commercially available reagents is significantly more efficient for covalent stabilisation of protein–protein interactions.

Detalles Bibliográficos
Autores principales: Foster, Simon R., Pearce, Alice, Blake, Alexander J., Welham, Melanie J., Dowden, James
Formato: Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2007
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141736/
https://www.ncbi.nlm.nih.gov/pubmed/17563813
http://dx.doi.org/10.1039/b701542a
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author Foster, Simon R.
Pearce, Alice
Blake, Alexander J.
Welham, Melanie J.
Dowden, James
author_facet Foster, Simon R.
Pearce, Alice
Blake, Alexander J.
Welham, Melanie J.
Dowden, James
author_sort Foster, Simon R.
collection PubMed
description A novel octavalent, resorcin[4]arene derived, cross-linker designed to overcome some of the limitations of commercially available reagents is significantly more efficient for covalent stabilisation of protein–protein interactions.
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spelling pubmed-21417362007-12-18 Novel octavalent cross-linker displays efficient trapping of protein–protein interactions Foster, Simon R. Pearce, Alice Blake, Alexander J. Welham, Melanie J. Dowden, James Chem Commun (Camb) Chemistry A novel octavalent, resorcin[4]arene derived, cross-linker designed to overcome some of the limitations of commercially available reagents is significantly more efficient for covalent stabilisation of protein–protein interactions. Royal Society of Chemistry 2007-06-28 2007-03-20 /pmc/articles/PMC2141736/ /pubmed/17563813 http://dx.doi.org/10.1039/b701542a Text en This journal is © The Royal Society of Chemistry 2007 http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Chemistry
Foster, Simon R.
Pearce, Alice
Blake, Alexander J.
Welham, Melanie J.
Dowden, James
Novel octavalent cross-linker displays efficient trapping of protein–protein interactions
title Novel octavalent cross-linker displays efficient trapping of protein–protein interactions
title_full Novel octavalent cross-linker displays efficient trapping of protein–protein interactions
title_fullStr Novel octavalent cross-linker displays efficient trapping of protein–protein interactions
title_full_unstemmed Novel octavalent cross-linker displays efficient trapping of protein–protein interactions
title_short Novel octavalent cross-linker displays efficient trapping of protein–protein interactions
title_sort novel octavalent cross-linker displays efficient trapping of protein–protein interactions
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141736/
https://www.ncbi.nlm.nih.gov/pubmed/17563813
http://dx.doi.org/10.1039/b701542a
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AT pearcealice noveloctavalentcrosslinkerdisplaysefficienttrappingofproteinproteininteractions
AT blakealexanderj noveloctavalentcrosslinkerdisplaysefficienttrappingofproteinproteininteractions
AT welhammelaniej noveloctavalentcrosslinkerdisplaysefficienttrappingofproteinproteininteractions
AT dowdenjames noveloctavalentcrosslinkerdisplaysefficienttrappingofproteinproteininteractions

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