Progressive Muscular Dystrophy in α-Sarcoglycan–deficient Mice

Limb-girdle muscular dystrophy type 2D (LGMD 2D) is an autosomal recessive disorder caused by mutations in the α-sarcoglycan gene. To determine how α-sarcoglycan deficiency leads to muscle fiber degeneration, we generated and analyzed α-sarcoglycan– deficient mice. Sgca-null mice developed progressi...

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Detalles Bibliográficos
Autores principales: Duclos, Franck, Straub, Volker, Moore, Steven A., Venzke, David P., Hrstka, Ron F., Crosbie, Rachelle H., Durbeej, Madeleine, Lebakken, Connie S., Ettinger, Audrey J., van der Meulen, Jack, Holt, Kathleen H., Lim, Leland E., Sanes, Joshua R., Davidson, Beverly L., Faulkner, John A., Williamson, Roger, Campbell, Kevin P.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141773/
https://www.ncbi.nlm.nih.gov/pubmed/9744877

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