STUDIES ON ENZYMATIC HISTOCHEMISTRY : XXVI. THE HISTOLOGICAL DISTRIBUTION OF CHOLINE ESTERASE IN THE GASTRIC MUCOSA NORMALLY AND AFTER ADMINISTRATION OF CERTAIN DRUGS

Extraction experiments demonstrated that choline esterase could be removed from microtome sections of tissue with as great facility by 0.9 per cent NaCl as by 30 per cent glycerol. The quantitative distribution of choline esterase through the wall of the pig stomach was studied, and it was found tha...

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Detalles Bibliográficos
Autor principal: Glick, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1938
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141942/
https://www.ncbi.nlm.nih.gov/pubmed/19873052
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author Glick, David
author_facet Glick, David
author_sort Glick, David
collection PubMed
description Extraction experiments demonstrated that choline esterase could be removed from microtome sections of tissue with as great facility by 0.9 per cent NaCl as by 30 per cent glycerol. The quantitative distribution of choline esterase through the wall of the pig stomach was studied, and it was found that the epithelial cell region possessed the greatest activity and muscle tissue the least. Pylorus was more active than fundus or cardia. The enzyme activities found were independent of the physiological state of the normal stomach at the time the animal was killed. Neither intramuscular injection of acetyl choline, eserine, nor atropine shortly before killing had significant influence upon the activity in any region of the stomach. The implications of these results were discussed.
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spelling pubmed-21419422008-04-23 STUDIES ON ENZYMATIC HISTOCHEMISTRY : XXVI. THE HISTOLOGICAL DISTRIBUTION OF CHOLINE ESTERASE IN THE GASTRIC MUCOSA NORMALLY AND AFTER ADMINISTRATION OF CERTAIN DRUGS Glick, David J Gen Physiol Article Extraction experiments demonstrated that choline esterase could be removed from microtome sections of tissue with as great facility by 0.9 per cent NaCl as by 30 per cent glycerol. The quantitative distribution of choline esterase through the wall of the pig stomach was studied, and it was found that the epithelial cell region possessed the greatest activity and muscle tissue the least. Pylorus was more active than fundus or cardia. The enzyme activities found were independent of the physiological state of the normal stomach at the time the animal was killed. Neither intramuscular injection of acetyl choline, eserine, nor atropine shortly before killing had significant influence upon the activity in any region of the stomach. The implications of these results were discussed. The Rockefeller University Press 1938-01-20 /pmc/articles/PMC2141942/ /pubmed/19873052 Text en Copyright © Copyright, 1938, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Glick, David
STUDIES ON ENZYMATIC HISTOCHEMISTRY : XXVI. THE HISTOLOGICAL DISTRIBUTION OF CHOLINE ESTERASE IN THE GASTRIC MUCOSA NORMALLY AND AFTER ADMINISTRATION OF CERTAIN DRUGS
title STUDIES ON ENZYMATIC HISTOCHEMISTRY : XXVI. THE HISTOLOGICAL DISTRIBUTION OF CHOLINE ESTERASE IN THE GASTRIC MUCOSA NORMALLY AND AFTER ADMINISTRATION OF CERTAIN DRUGS
title_full STUDIES ON ENZYMATIC HISTOCHEMISTRY : XXVI. THE HISTOLOGICAL DISTRIBUTION OF CHOLINE ESTERASE IN THE GASTRIC MUCOSA NORMALLY AND AFTER ADMINISTRATION OF CERTAIN DRUGS
title_fullStr STUDIES ON ENZYMATIC HISTOCHEMISTRY : XXVI. THE HISTOLOGICAL DISTRIBUTION OF CHOLINE ESTERASE IN THE GASTRIC MUCOSA NORMALLY AND AFTER ADMINISTRATION OF CERTAIN DRUGS
title_full_unstemmed STUDIES ON ENZYMATIC HISTOCHEMISTRY : XXVI. THE HISTOLOGICAL DISTRIBUTION OF CHOLINE ESTERASE IN THE GASTRIC MUCOSA NORMALLY AND AFTER ADMINISTRATION OF CERTAIN DRUGS
title_short STUDIES ON ENZYMATIC HISTOCHEMISTRY : XXVI. THE HISTOLOGICAL DISTRIBUTION OF CHOLINE ESTERASE IN THE GASTRIC MUCOSA NORMALLY AND AFTER ADMINISTRATION OF CERTAIN DRUGS
title_sort studies on enzymatic histochemistry : xxvi. the histological distribution of choline esterase in the gastric mucosa normally and after administration of certain drugs
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141942/
https://www.ncbi.nlm.nih.gov/pubmed/19873052
work_keys_str_mv AT glickdavid studiesonenzymatichistochemistryxxvithehistologicaldistributionofcholineesteraseinthegastricmucosanormallyandafteradministrationofcertaindrugs

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