THE INFLUENCE OF THE MOLECULAR WEIGHT OF ANTIGEN ON THE PROPORTION OF ANTIBODY TO ANTIGEN IN PRECIPITATES : II. A STATISTICAL EXAMINATION OF AVAILABLE DATA, INCLUDING SOME PREVIOUSLY UNPUBLISHED

A statistical examination of the available data on the ratio of antibody to antigen in specific precipitates made at or near the optimum shows a definite correlation between the ratio and the molecular weight of antigen (regression coefficient = –0.529 (±0.014)). The authors' assumption that at...

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Detalles Bibliográficos
Autores principales: Boyd, William C., Hooker, Sanford B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1939
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141996/
https://www.ncbi.nlm.nih.gov/pubmed/19873104
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author Boyd, William C.
Hooker, Sanford B.
author_facet Boyd, William C.
Hooker, Sanford B.
author_sort Boyd, William C.
collection PubMed
description A statistical examination of the available data on the ratio of antibody to antigen in specific precipitates made at or near the optimum shows a definite correlation between the ratio and the molecular weight of antigen (regression coefficient = –0.529 (±0.014)). The authors' assumption that at this point the antigen molecules are just about covered by a layer of antibody behaving as contiguous spherical ("Svedberg") units of weight 35,200 leads to predicted ratios that in general agree well with those found, though individual experimental determinations may deviate considerably.
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spelling pubmed-21419962008-04-23 THE INFLUENCE OF THE MOLECULAR WEIGHT OF ANTIGEN ON THE PROPORTION OF ANTIBODY TO ANTIGEN IN PRECIPITATES : II. A STATISTICAL EXAMINATION OF AVAILABLE DATA, INCLUDING SOME PREVIOUSLY UNPUBLISHED Boyd, William C. Hooker, Sanford B. J Gen Physiol Article A statistical examination of the available data on the ratio of antibody to antigen in specific precipitates made at or near the optimum shows a definite correlation between the ratio and the molecular weight of antigen (regression coefficient = –0.529 (±0.014)). The authors' assumption that at this point the antigen molecules are just about covered by a layer of antibody behaving as contiguous spherical ("Svedberg") units of weight 35,200 leads to predicted ratios that in general agree well with those found, though individual experimental determinations may deviate considerably. The Rockefeller University Press 1939-01-20 /pmc/articles/PMC2141996/ /pubmed/19873104 Text en Copyright © Copyright, 1939, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Boyd, William C.
Hooker, Sanford B.
THE INFLUENCE OF THE MOLECULAR WEIGHT OF ANTIGEN ON THE PROPORTION OF ANTIBODY TO ANTIGEN IN PRECIPITATES : II. A STATISTICAL EXAMINATION OF AVAILABLE DATA, INCLUDING SOME PREVIOUSLY UNPUBLISHED
title THE INFLUENCE OF THE MOLECULAR WEIGHT OF ANTIGEN ON THE PROPORTION OF ANTIBODY TO ANTIGEN IN PRECIPITATES : II. A STATISTICAL EXAMINATION OF AVAILABLE DATA, INCLUDING SOME PREVIOUSLY UNPUBLISHED
title_full THE INFLUENCE OF THE MOLECULAR WEIGHT OF ANTIGEN ON THE PROPORTION OF ANTIBODY TO ANTIGEN IN PRECIPITATES : II. A STATISTICAL EXAMINATION OF AVAILABLE DATA, INCLUDING SOME PREVIOUSLY UNPUBLISHED
title_fullStr THE INFLUENCE OF THE MOLECULAR WEIGHT OF ANTIGEN ON THE PROPORTION OF ANTIBODY TO ANTIGEN IN PRECIPITATES : II. A STATISTICAL EXAMINATION OF AVAILABLE DATA, INCLUDING SOME PREVIOUSLY UNPUBLISHED
title_full_unstemmed THE INFLUENCE OF THE MOLECULAR WEIGHT OF ANTIGEN ON THE PROPORTION OF ANTIBODY TO ANTIGEN IN PRECIPITATES : II. A STATISTICAL EXAMINATION OF AVAILABLE DATA, INCLUDING SOME PREVIOUSLY UNPUBLISHED
title_short THE INFLUENCE OF THE MOLECULAR WEIGHT OF ANTIGEN ON THE PROPORTION OF ANTIBODY TO ANTIGEN IN PRECIPITATES : II. A STATISTICAL EXAMINATION OF AVAILABLE DATA, INCLUDING SOME PREVIOUSLY UNPUBLISHED
title_sort influence of the molecular weight of antigen on the proportion of antibody to antigen in precipitates : ii. a statistical examination of available data, including some previously unpublished
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2141996/
https://www.ncbi.nlm.nih.gov/pubmed/19873104
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