THE EFFECT OF TEMPERATURE ON THE RATE OF HYDROLYSIS OF TRIGLYCERIDES BY PANCREATIC LIPASE

1. The temperature characteristics for the hydrolysis of various concentrations of tributyrin, trivalerin, tricaproin, triheptylin, and tricaprylin have been determined. 2. The µ values for the hydrolysis of all concentrations of tributyrin by pancreatic lipase, except the most dilute, were found to be constant within the experimental error, 8,500 ± 1,000. 3. The temperature characteristics for the hydrolysis of trivalerin, tricaproin, triheptylin, and tricaprylin varied from approximately 8,500 ± 1,000 for the high concentrations to 12,400, 20,000, 22,400, and 23,700 respectively for the most dilute concentration of each. 4. An interpretation of these results was presented.