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NATURE OF THE GROWTH FACTOR FOR THE COLORLESS ALGA PROTOTHECA ZOPFII
Barker's study on the nutritive requirements of Prototheca zopfii indicated that this colorless alga fails to grow in the absence of small amounts of yeast extract. A study of the growth factor requirements of Prototheca has shown that the active constituent of yeast extract necessary for the g...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
1945
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2142673/ https://www.ncbi.nlm.nih.gov/pubmed/19873421 |
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author | Anderson, Edward H. |
author_facet | Anderson, Edward H. |
author_sort | Anderson, Edward H. |
collection | PubMed |
description | Barker's study on the nutritive requirements of Prototheca zopfii indicated that this colorless alga fails to grow in the absence of small amounts of yeast extract. A study of the growth factor requirements of Prototheca has shown that the active constituent of yeast extract necessary for the growth of this organism is thiamin (vitamin B(1)). Thiamin can fully replace the complex yeast material and allows, in the basal medium used, a maximum cell yield in concentrations of 1–3 x 10(–7) M. Thiamin as such, however, is not essential for the growth of Prototheca zopfii. The alga can develop equally well if supplied with both the thiazole and pyrimidine constituents of this vitamin. These appear to be needed in equimolar proportions. Maximum cell yield is obtained with 3 x 10(–8) M concentrations of the two components. |
format | Text |
id | pubmed-2142673 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1945 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21426732008-04-23 NATURE OF THE GROWTH FACTOR FOR THE COLORLESS ALGA PROTOTHECA ZOPFII Anderson, Edward H. J Gen Physiol Article Barker's study on the nutritive requirements of Prototheca zopfii indicated that this colorless alga fails to grow in the absence of small amounts of yeast extract. A study of the growth factor requirements of Prototheca has shown that the active constituent of yeast extract necessary for the growth of this organism is thiamin (vitamin B(1)). Thiamin can fully replace the complex yeast material and allows, in the basal medium used, a maximum cell yield in concentrations of 1–3 x 10(–7) M. Thiamin as such, however, is not essential for the growth of Prototheca zopfii. The alga can develop equally well if supplied with both the thiazole and pyrimidine constituents of this vitamin. These appear to be needed in equimolar proportions. Maximum cell yield is obtained with 3 x 10(–8) M concentrations of the two components. The Rockefeller University Press 1945-03-20 /pmc/articles/PMC2142673/ /pubmed/19873421 Text en Copyright © Copyright, 1945, by The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Anderson, Edward H. NATURE OF THE GROWTH FACTOR FOR THE COLORLESS ALGA PROTOTHECA ZOPFII |
title | NATURE OF THE GROWTH FACTOR FOR THE COLORLESS ALGA PROTOTHECA ZOPFII |
title_full | NATURE OF THE GROWTH FACTOR FOR THE COLORLESS ALGA PROTOTHECA ZOPFII |
title_fullStr | NATURE OF THE GROWTH FACTOR FOR THE COLORLESS ALGA PROTOTHECA ZOPFII |
title_full_unstemmed | NATURE OF THE GROWTH FACTOR FOR THE COLORLESS ALGA PROTOTHECA ZOPFII |
title_short | NATURE OF THE GROWTH FACTOR FOR THE COLORLESS ALGA PROTOTHECA ZOPFII |
title_sort | nature of the growth factor for the colorless alga prototheca zopfii |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2142673/ https://www.ncbi.nlm.nih.gov/pubmed/19873421 |
work_keys_str_mv | AT andersonedwardh natureofthegrowthfactorforthecolorlessalgaprotothecazopfii |